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TNO 6

Known as: TNO-6 
National Institutes of Health

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1 relation

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spiroplatin

Papers overview

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2004
2004
Phase I study of the cisplatin analogue 1,1-diamminomethylcyclohexane sulfatoplatinum (TNO-6) (NSC 311056)
SummaryThe cisplatin derivative TNO-6 was evaluated for clinical toxicity in a phase I trial. TNO-6 was given daily for 5 days… 
1993
1993
Prevention of home related injuries of pre-school children: safety measures taken by mothers.
Home related injuries are a major threat to the health of pre-school children in the Netherlands. Many risk situations can only… 
1988
1988
Pharmacokinetics of free and total platinum species after rapid and prolonged infusions of aqua (1,1-bis(aminomethyl)cyclohexane) sulfatoplatinum (II) (spiroplatin) during a phase I trial.
1987
1987
Korrekturprinzipien der einseitigen Aphakie zum Erhalt der Binokularfunktionen
Basierend auf Untersuchungen zur binokularen Aniseikonietoleranz wurde ein Konzept fur die Korrektur der einseitigen Aphakie bei… 
1986
1986
TNO-6 has no effect in gastrointestinal cancer:N-acetyl-glucosaminidase shows renal damage
Twenty-five patients, 16 with gastric cancer and nine with colonic cancer, received TNO-6 30 mg m−2 every four weeks. No… 
1986
1986
Ligands of second generation platinum analogs decrease both platinum-induced DNA cross-linking and its ability to interact with 1-beta-D-arabinofuranosyl cytosine to potentiate cytotoxic efficacy.
1985
1985
TNO‐6‐induced acute renal failure. A case report
A case of fatal acute renal failure during treatment with 1,1‐diaminomethyl cyclohexane sulphato platinum II (TNO‐6) is reported… 
1984
1984
Clinical Experience with 1, 1-Diaminomethylcyclohexane (Sulphato) Platinum (II) (TNO-6)
Cis-diamminodichloroplatinum II (cisplatin) is the first member of a group of platinum coordination complexes, which were shown… 
1984
1984
Influence of hydrolysis products of aqua(1,1-bis(aminomethyl)cyclohexane)sulfatoplatinum(II) on toxicity in rats.
1983
1983
Antitumor activity, induction of cross-resistance, and nephrotoxicity of a new platinum analogue, cis-1,1-diaminomethylcyclohexaneplatinum(II) sulfate, and of cis-diamminedichloroplatinum(II) in an…
A newly synthesized platinum analogue, cis-1,1-diaminomethylcyclohexaneplatinum(II) sulfate (TNO-6), was compared with cis… 
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