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TNO 6

Known as: TNO-6 
National Institutes of Health

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1 relation

Broader (1)

spiroplatin

Papers overview

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2004
2004
Phase I study of the cisplatin analogue 1,1-diamminomethylcyclohexane sulfatoplatinum (TNO-6) (NSC 311056)
SummaryThe cisplatin derivative TNO-6 was evaluated for clinical toxicity in a phase I trial. TNO-6 was given daily for 5 days… 
1993
1993
Prevention of home related injuries of pre-school children: safety measures taken by mothers.
Home related injuries are a major threat to the health of pre-school children in the Netherlands. Many risk situations can only… 
1988
1988
Pharmacokinetics of free and total platinum species after rapid and prolonged infusions of aqua (1,1-bis(aminomethyl)cyclohexane) sulfatoplatinum (II) (spiroplatin) during a phase I trial.
1987
1987
Preclinical toxicology of platinum analogues in dogs.
1987
1987
Korrekturprinzipien der einseitigen Aphakie zum Erhalt der Binokularfunktionen
Basierend auf Untersuchungen zur binokularen Aniseikonietoleranz wurde ein Konzept fur die Korrektur der einseitigen Aphakie bei… 
1986
1986
TNO-6 has no effect in gastrointestinal cancer:N-acetyl-glucosaminidase shows renal damage
Twenty-five patients, 16 with gastric cancer and nine with colonic cancer, received TNO-6 30 mg m−2 every four weeks. No… 
1986
1986
Ligands of second generation platinum analogs decrease both platinum-induced DNA cross-linking and its ability to interact with 1-beta-D-arabinofuranosyl cytosine to potentiate cytotoxic efficacy.
1984
1984
Clinical Experience with 1, 1-Diaminomethylcyclohexane (Sulphato) Platinum (II) (TNO-6)
Cis-diamminodichloroplatinum II (cisplatin) is the first member of a group of platinum coordination complexes, which were shown… 
1984
1984
Influence of hydrolysis products of aqua(1,1-bis(aminomethyl)cyclohexane)sulfatoplatinum(II) on toxicity in rats.
1983
1983
Antitumor activity, induction of cross-resistance, and nephrotoxicity of a new platinum analogue, cis-1,1-diaminomethylcyclohexaneplatinum(II) sulfate, and of cis-diamminedichloroplatinum(II) in an…
A newly synthesized platinum analogue, cis-1,1-diaminomethylcyclohexaneplatinum(II) sulfate (TNO-6), was compared with cis… 
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