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Purpose: Reduced uninvolved immunoglobulin (Ig) levels are a hallmark of multiple myeloma. We previously showed that B-cell… Expand OBJECTIVE
This study aims to investigate the role of T follicular helper (TFH) cells in the immunopathogenesis of pediatric… Expand B-cell activating factor (BAFF), also known as tumour necrosis factor (TNF) ligand superfamily member 13B, is an important immune… Expand IntroductionB-lymphocyte stimulator (BLyS) and a proliferation-inducing ligand (APRIL) are members of the tumor necrosis factor… Expand The survival of transitional and mature B cells requires both the B cell antigen receptor (BCR) and BLyS receptor 3 (BR3), which… Expand B lymphocyte stimulator (BLyS), also known as B cell-activating factor, is a key positive regulator of B cell homeostasis, and… Expand The c-Myb transcription factor is crucial during definitive hematopoiesis. However, the embryonic lethality of Myb traditional… Expand Summary: B cells complete maturation after migrating to the periphery, where they transit several intermediate developmental… Expand BAFF/BLyS, a member of the tumor necrosis family (TNF) superfamily of ligands, is a crucial survival factor for B cells. BAFF… Expand The TNF-like ligand BAFF/BLyS is a potent survival factor for B cells. It binds three receptors: TACI, BCMA, and BR3. We show… Expand