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TNFRSF12A wt Allele

Known as: FN14, Tumor Necrosis Factor Receptor Superfamily, Member 12A wt Allele, CD266 
Human TNFRSF12A wild-type allele is located in the vicinity of 16p13.3 and is approximately 4 kb in length. This allele, which encodes tumor necrosis… 
National Institutes of Health

Related topics

Related topics

9 relations
16p13.3ApoptosisCell SurvivalCytokine Signaling Process

Papers overview

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2018
2018
TWEAK / Fn 14 pathway modulates properties of a human microvascular endothelial cell model of blood brain barrier
Background: The TNF ligand family member TWEAK exists as membrane and soluble forms and is involved in the regulation of various… 
2017
2017
The Cytotoxicity and Action of Curcumin Derivatives against Fn14+ Triple Negative Breast Cancer through repression of NF-κB p65
2017
2017
Fn 14 $ TRAIL fusion protein is oligomerized by TWEAK into a superef fi cient TRAIL analog
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) demonstrates specific anti-cancer activity, but insufficient… 
2016
2016
Fn14 is regulated via the RhoA pathway and mediates nuclear factor-kappaB activation by Angiotensin II.
Angiotesin II (Ang II) plays an important role in cardiac remodeling. Fibroblast growth factor inducible-14 (Fn14) is the… 
2016
2016
Moderated Poster Session - Heart
Background: Myocarditis, defined as an inflammation of the myocardium, can be caused by autoimmune reactions. To study these… 
2015
2015
TWEAK / Fn 14 interaction regulates RANTES production , BMP-2-induced differentiation , and RANKL expression in mouse osteoblastic MC 3 T 3E 1 cells
Tumour necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK), a member of the TNF family, is a multifunctional cytokine… 
2014
2014
Abstract 4512: Construction and characterization of novel, human serine protease granzyme B-based cancer therapeutics targeting the TNFR family member Fn14
The TNF superfamily cytokine TWEAK and its receptor Fn14 have emerged as potentially clinically valuable targets for cancer… 
2012
2012
Efectos de Tweak dependientes de NF-KB en la célula tubular renal
Durante el fracaso renal agudo parenquimatoso se produce un proceso inflamatorio que intenta reparar el dano tisular, pero que a… 
2006
2006
Methods and compositions for modulating tweak and fn14 activity
Agonists and antagonists which modulate the activity of TWEAK and TWEAK receptor are provided. The methods, compositions and kits… 
2006
2006
Anticorps de type agonistes qui se lient au recepteur tweak fn14 et modulent par consequent les phenotypes associes a l'adiposite, et leur utilisation a des fins therapeutiques
L'invention concerne des agonistes du recepteur Fn14, ainsi que leur utilisation pour activer la voie de signalisation du… 
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