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TNFRSF12A wt Allele

Known as: FN14, Tumor Necrosis Factor Receptor Superfamily, Member 12A wt Allele, CD266 
Human TNFRSF12A wild-type allele is located in the vicinity of 16p13.3 and is approximately 4 kb in length. This allele, which encodes tumor necrosis… 
National Institutes of Health

Related topics

Related topics

9 relations
16p13.3ApoptosisCell SurvivalCytokine Signaling Process

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
FN14 Blockade on Pulmonary Microvascular Endothelial Cells Improves the Outcome of Sepsis-Induced Acute Lung Injury
ABSTRACT Pulmonary microvascular leakage is one of the characteristics of blood–air barrier dysfunction in septic acute lung… 
2016
2016
Non-canonical NFκB activation promotes chemokine expression in podocytes
TNF-like weak inducer of apoptosis (TWEAK) receptor Fn14 is expressed by podocytes and Fn14 deficiency protects from experimental… 
2016
2016
Fn14 deficiency protects lupus‐prone mice from histological lupus erythematosus‐like skin inflammation induced by ultraviolet light
The cytokine TNF‐like weak inducer of apoptosis (TWEAK) and its receptor Fn14 are involved in cell survival and cytokine… 
2016
2016
Abstract 1210: Preclinical pharmacology and repeated dose toxicity of the novel agonistic TWEAK receptor binding antibody BAY-356
TWEAK receptor (TWEAKR, FN14) is a member of the tumor necrosis factor receptor superfamiliy and is highly expressed in a variety… 
2016
2016
Fn14 is regulated via the RhoA pathway and mediates nuclear factor-kappaB activation by Angiotensin II.
Angiotesin II (Ang II) plays an important role in cardiac remodeling. Fibroblast growth factor inducible-14 (Fn14) is the… 
Review
2012
Review
2012
The TWEAK-Fn14 System: Breaking the Silence of Cytokine-Induced Skeletal Muscle Wasting
The occurrence of skeletal muscle atrophy, a devastating complication of a large number of disease states and inactivity/disuse… 
2010
2010
The Effects of TWEAK, Fn14, and TGF-beta1 on Degeneration of Human Intervertebral Disc.
OBJECTIVE The purpose of this study is to explain the effect and reciprocal action among tumor necrosis factor (TNF) like weak… 
2010
2010
[The expression of TWEAKR/Fn14 in Rheumatoid arthritis fibroblast-like synoviocytes].
AIM To investigate the mechanism of TWEAK on Rheumatoid arthritis fibroblast-like synoviocytes (RA FLS) activation and articular… 
2006
2006
Expression of TWEAK and its receptor Fn14 in human subcutaneous adipose tissue. Relationship with other inflammatory cytokines in obesity.
2006
2006
TWEAK shall inherit the earth
Sometimes size really does not matter: recent papers on the tumour necrosis factor (TNF)-like ligand, TWEAK (tumour necrosis… 
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