Skip to search formSkip to main contentSkip to account menu

TNF wt Allele

Known as: DIF, TNF, Macrophage-Derived Gene, Tumor Necrosis Factor Gene 
Human TNF wild-type allele is located in the vicinity of 6p21.3 and is approximately 3 kb in length. This allele, which encodes tumor necrosis factor… 
National Institutes of Health

Related topics

Related topics

36 relations
6p21.3Adipocytokine Signaling PathwayAngiogenic ProcessApoptosis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Tumor necrosis factor and lymphotoxin-alpha polymorphisms and severe malaria in African populations.
The tumor necrosis factor gene (TNF) and lymphotoxin-alpha gene (LTA) have long attracted attention as candidate genes for… 
Highly Cited
2007
Highly Cited
2007
Regulation of Tumor Cell Sensitivity to TRAIL-Induced Apoptosis by the Metastatic Suppressor Raf Kinase Inhibitor Protein via Yin Yang 1 Inhibition and Death Receptor 5 Up-Regulation
Raf-1 kinase inhibitor protein (RKIP) has been implicated in the regulation of cell survival pathways and metastases, and is… 
2006
2006
Induced focal adhesion kinase expression suppresses apoptosis by activating NF-kappaB signaling in intestinal epithelial cells.
Focal adhesion kinase (FAK) integrates various extracellular and intracellular signals and is implicated in a variety of… 
Highly Cited
2004
Highly Cited
2004
PEG10 activation by co-stimulation of CXCR5 and CCR7 essentially contributes to resistance to apoptosis in CD19+CD34+ B cells from patients with B cell lineage acute and chronic lymphocytic leukemia.
We investigated CD19+CD34+ and CD19+CD34- B cells from cord blood (CB) and typical patients with B cell lineage acute and chronic… 
Highly Cited
2003
Highly Cited
2003
Linkage of mild malaria to the major histocompatibility complex in families living in Burkina Faso.
Tumor necrosis factor alpha (TNF alpha) is thought to be a critical mediator of malaria fever, and mild malaria was previously… 
Highly Cited
2002
Highly Cited
2002
Growth factor rescue of cytokine mediated trophoblast apoptosis.
INTRODUCTION Apoptosis can be induced in cytotrophoblasts and syncytiotrophoblast in culture by a combination of TNF-alpha and… 
Highly Cited
2001
Highly Cited
2001
Lipoxin A4 and Aspirin-Triggered 15-Epi-Lipoxin A4 Antagonize TNF-α-Stimulated Neutrophil-Enterocyte Interactions In Vitro and Attenuate TNF-α-Induced Chemokine Release and Colonocyte Apoptosis in…
Lipoxins (LXs) are lipoxygenase-derived eicosanoids and putative endogenous braking signals for inflammation in the… 
2001
2001
Bacterial peptidoglycan-induced tnf-alpha transcription is mediated through the transcription factors Egr-1, Elk-1, and NF-kappaB.
Bacteria and their ubiquitous cell wall component peptidoglycan (PGN) activate the innate immune system of the host and induce… 
Highly Cited
2000
Highly Cited
2000
Thioredoxin prolongs survival of B-type chronic lymphocytic leukemia cells.
Thioredoxin (Trx) is a ubiquitous protein disulfide oxidoreductase with antioxidant, cytokine, and chemotactic properties… 
Review
1992
Review
1992
Application of transcriptional and posttranscriptional reporter constructs to the analysis of tumor necrosis factor gene regulation.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)