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TNF wt Allele

Known as: DIF, TNF, Macrophage-Derived Gene, Tumor Necrosis Factor Gene 
Human TNF wild-type allele is located in the vicinity of 6p21.3 and is approximately 3 kb in length. This allele, which encodes tumor necrosis factor… Expand
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Susceptibility to infectious diseases is influenced by genetic background and efficient cellular immune activation is responsible… Expand
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Highly Cited
2007
Highly Cited
2007
Tumors actively develop different mechanisms such as immunosuppressive cytokine production to escape from immune control and… Expand
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Highly Cited
2004
Highly Cited
2004
IL-6 and TNF-alpha have been associated with insulin resistance and type 2 diabetes. Furthermore, abnormalities in muscle fatty… Expand
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Highly Cited
2001
Highly Cited
2001
Human hepatocytes usually are resistant to TNF-α cytotoxicity. In mouse or rat hepatocytes, repression of NF-κB activation is… Expand
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Highly Cited
2000
Highly Cited
2000
The hepatitis C virus (HCV) core protein is a multifunctional protein. It may bind to the death domain of tumor necrosis factor… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND & AIMS Tumor necrosis factor (TNF) is considered to play an important role in the pathogenesis of Crohn's disease (CD… Expand
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Highly Cited
1997
Highly Cited
1997
Since the tumor necrosis factor alpha (TNF-alpha) gene was found to be located in the central major histocompatibility complex… Expand
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Highly Cited
1997
Highly Cited
1997
Tumor necrosis factor-alpha (TNF-alpha) production by adipocytes is elevated in obesity, as shown by increased adipose tissue TNF… Expand
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Highly Cited
1996
Highly Cited
1996
Tumor necrosis factor alpha (TNF-alpha) signaling gives rise to a number of events, including activation of transcription factor… Expand
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Highly Cited
1991
Highly Cited
1991
Pentoxifylline decreases lung injury after intravenous endotoxin; the mechanism is unknown. Tumor necrosis factor-alpha (TNF) is… Expand
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