TMEM173 gene

Known as: STING, MEDIATOR OF IRF3 ACTIVATION, MITA 
This gene plays a role in the immune response.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Detection of evolutionarily conserved molecules on microbial pathogens by host immune sensors represents the initial trigger of… (More)
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 4
Is this relevant?
Highly Cited
2013
Highly Cited
2013
Activation of the stimulator of interferon genes (STING) pathway by microbial or self-DNA, as well as cyclic dinucleotides (CDNs… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2013
Highly Cited
2013
The presence of DNA in the cytoplasm of mammalian cells is a danger signal that triggers host immune responses such as the… (More)
  • figure 2
  • figure 3
  • figure 4
  • figure 5
  • figure 6
Is this relevant?
Highly Cited
2012
Highly Cited
2012
The induction of type I interferons by the bacterial secondary messengers cyclic di-GMP (c-di-GMP) or cyclic di-AMP (c-di-AMP) is… (More)
Is this relevant?
Highly Cited
2011
Highly Cited
2011
The innate immune system detects infection by using germline-encoded receptors that are specific for conserved microbial… (More)
Is this relevant?
Highly Cited
2010
Highly Cited
2010
Macrophages respond to cytosolic nucleic acids by activating cysteine protease caspase-1 within a complex called the inflammasome… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2010
Highly Cited
2010
The detection of intracellular microbial DNA is critical to appropriate innate immune responses; however, knowledge of how such… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2010
Highly Cited
2010
The innate immune system detects pathogen- and host-derived double-stranded DNA exposed to the cytosol and induces type I… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2009
Highly Cited
2009
The innate immune system is critical for the early detection of invading pathogens and for initiating cellular host defence… (More)
  • figure 1
  • figure 3
  • figure 2
  • figure 4
Is this relevant?
Highly Cited
2004
Highly Cited
2004
PURPOSE With the advent of tissue bulking agents, in particular dextranomer/hyaluronic acid copolymer (Dx/HA), for endoscopic… (More)
Is this relevant?