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Growth phase-dependent variation in protein composition of the Escherichia coli nucleoid.
The genome DNA of Escherichia coli is associated with about 10 DNA-binding structural proteins, altogether forming the nucleoid. The nucleoid proteins play some functional roles, besides theirExpand
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Functional modulation of Escherichia coli RNA polymerase.
  • A. Ishihama
  • Medicine, Biology
  • Annual review of microbiology
  • 2000
The promoter recognition specificity of Escherichia coli RNA polymerase is modulated by replacement of the sigma subunit in the first step and by interaction with transcription factors in the secondExpand
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Functional Characterization in Vitro of All Two-component Signal Transduction Systems from Escherichia coli*
Bacteria possess a signal transduction system, referred to as a two-component system, for adaptation to external stimuli. Each two-component system consists of a sensor protein-histidine kinase (HK)Expand
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Twelve Species of the Nucleoid-associated Protein from Escherichia coli
The genome of Escherichia coli is composed of a single molecule of circular DNA with the length of about 47,000 kilobase pairs, which is associated with about 10 major DNA-binding proteins,Expand
  • 407
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A third recognition element in bacterial promoters: DNA binding by the alpha subunit of RNA polymerase.
A DNA sequence rich in (A+T), located upstream of the -10, -35 region of the Escherichia coli ribosomal RNA promoter rrnB P1 and called the UP element, stimulates transcription by a factor of 30 inExpand
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Competition among seven Escherichia coli sigma subunits: relative binding affinities to the core RNA polymerase.
Seven different species of the RNA polymerase sigma subunit exist in Escherichia coli, each binding to a single species of the core enzyme and thereby directing transcription of a specific set ofExpand
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Regulation of RNA polymerase sigma subunit synthesis in Escherichia coli: intracellular levels of four species of sigma subunit under various growth conditions.
By a quantitative Western immunoblot analysis, the intracellular levels of two principal sigma subunits, sigma 70 (sigma D, the rpoD gene product) and sigma 38 (sigma S, the rpoS gene product), andExpand
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A stationary phase protein in Escherichia coli with binding activity to the major sigma subunit of RNA polymerase.
Switching of the transcription pattern in Escherichia coli during the growth transition from exponential to stationary phase is accompanied by the replacement of the RNA polymerase-associated sigma70Expand
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Transcriptional response of Escherichia coli to external copper
Transcriptional response of Escherichia coli upon exposure to external copper was studied using DNA microarray and in vivo and in vitro transcription assays. Transcription of threeExpand
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A regulatory trade-off as a source of strain variation in the species Escherichia coli.
There are few existing indications that strain variation in prokaryotic gene regulation is common or has evolutionary advantage. In this study, we report on isolates of Escherichia coli with distinctExpand
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