TMEM173 wt Allele

Known as: FLJ38577, MITA, MPYS 
Human TMEM173 wild-type allele is located in the vicinity of 5q31.2 and is approximately 7 kb in length. This allele, which encodes transmembrane… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1989-2018
0204019892018

Papers overview

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Highly Cited
2014
Highly Cited
2014
Ionizing radiation-mediated tumor regression depends on type I interferon (IFN) and the adaptive immune response, but several… (More)
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Highly Cited
2013
Highly Cited
2013
The presence of DNA in the cytoplasm of mammalian cells is a danger signal that triggers host immune responses such as the… (More)
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Highly Cited
2013
Highly Cited
2013
Double-stranded DNA (dsDNA) derived from pathogen- or host-damaged cells triggers innate immune responses when exposed to… (More)
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Highly Cited
2012
Highly Cited
2012
Cytosolic double-stranded DNA (dsDNA) stimulates the production of type I interferon (IFN) through the endoplasmic reticulum (ER… (More)
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Highly Cited
2011
Highly Cited
2011
The innate immune system detects infection by using germline-encoded receptors that are specific for conserved microbial… (More)
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Highly Cited
2011
Highly Cited
2011
The recognition of pathogenic DNA is important to the initiation of antiviral responses. Here we report the identification of… (More)
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Highly Cited
2009
Highly Cited
2009
We report here the identification and characterization of a protein, ERIS, an endoplasmic reticulum (ER) IFN stimulator, which is… (More)
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Highly Cited
2008
Highly Cited
2008
The cellular innate immune system is essential for recognizing pathogen infection and for establishing effective host defence… (More)
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Highly Cited
2008
Highly Cited
2008
Viral infection triggers activation of transcription factors such as NF-kappaB and IRF3, which collaborate to induce type I… (More)
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Highly Cited
2008
Highly Cited
2008
Although the best-defined function of type II major histocompatibility complex (MHC-II) is presentation of antigenic peptides to… (More)
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