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TMC 114

Known as: 114, TMC, TMC-114, TMC114 
 
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
OBJECTIVE This paper presents the final analysis of once-daily darunavir/ritonavir (DRV/r) vs. lopinavir/ritonavir (LPV/r) in… Expand
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Highly Cited
2009
Highly Cited
2009
OBJECTIVE Present 96-week data from ongoing ARTEMIS (AntiRetroviral Therapy with TMC114 ExaMined In Naive Subjects) trial… Expand
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Highly Cited
2008
Highly Cited
2008
BACKGROUND The present primary analysis of AntiRetroviral Therapy with TMC114 ExaMined In naive Subjects (ARTEMIS) compares the… Expand
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Highly Cited
2007
Highly Cited
2007
The high incidence of cross-resistance between human immunodeficiency virus type 1 (HIV-1) protease inhibitors (PIs) limits their… Expand
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Highly Cited
2007
Highly Cited
2007
The V82F/I84V double mutation is considered as the key residue mutation of the HIV-1 protease drug resistance because it can… Expand
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Review
2007
Review
2007
Darunavir (TMC114) is a newly developed HIV-1 protease inhibitor with potent antiviral activity against both wild-type and… Expand
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Highly Cited
2007
Highly Cited
2007
OBJECTIVE In POWER 1 and POWER 2, darunavir (TMC114) with low-dose ritonavir (darunavir/r) demonstrated greater efficacy versus… Expand
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Highly Cited
2005
Highly Cited
2005
The purpose of this study was to characterize the antiviral activity, cytotoxicity, and mechanism of action of TMC114, a novel… Expand
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Highly Cited
2005
Highly Cited
2005
The screening of known HIV-1 protease inhibitors against a panel of multi-drug-resistant viruses revealed the potent activity of… Expand
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Highly Cited
2003
Highly Cited
2003
We designed, synthesized, and identified UIC-94017 (TMC114), a novel nonpeptidic human immunodeficiency virus type 1 (HIV-1… Expand
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