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TMC 114

Known as: 114, TMC, TMC-114, TMC114 
National Institutes of Health

Related topics

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2 relations

Broader (2)

darunavirdarunavir ethanolate

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Pharmacokinetic Interaction between Indinavir and Darunavir with Low-Dose Ritonavir in Healthy Volunteers
Objective: To investigate the potential for a pharmacokinetic interaction between darunavir (DRV, TMC114, Prezista®), indinavir… 
2007
2007
No patient left behind—better treatments for resistant HIV infection
2007
2007
Prediction of clinical benefits of ritonavir‐boosted TMC114 from treatment effects on CD4 counts and HIV RNA
The aim of the study was to predict reductions in progression to AIDS/death associated with the treatment benefit of… 
2006
2006
Successful rescue therapy with darunabir (TMC114) in HIV-infected patients who have failed several ritonavir-boosted protease inhibitors
Darunabir, formerly TMC114, is a new protease inhibitor (PI) under clinical development designed to be active against HIV strains… 
Review
2006
Review
2006
Screening and selecting for optimized antiretroviral drugs: rising to the challenge of drug resistance
ABSTRACT Background: Resistance to antiretroviral (ARV) drugs constitutes one of the greatest limitations to effective long-term… 
2006
2006
Transport characteristics of the HIV protease inhibitor darunavir (TMC114) in Caco-2 monolayers
2006
2006
Prezista (darunavir, TMC-114) approved; may be important treatment advance.
A major new antiretroviral has been approved, for patients resistant to more than one protease inhibitor. There is no information… 
Review
2005
Review
2005
New targets and new drugs in the treatment of HIV.
Review
2004
Review
2004
TMC-114 (Tibotec).
Tibotec (formerly Tibotec-Virco) is developing TMC-114 as a potential treatment for HIV-1 infection. In February 2001, TMC-126… 
2003
2003
Gateways to clinical trials. March 2003.
Gateways to clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the… 
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