TLX1 gene

Known as: T-Cell Leukemia, Homeobox 1 Gene, HOMEOBOX 11, T-CELL LEUKEMIA 3 GENE 
This gene plays a role in transcriptional regulation and organogenesis. Translocations in the gene are associated with acute T-cell leukemia.

Topic mentions per year

Topic mentions per year

1989-2018
0119892018

Papers overview

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2013
2013
INTRODUCTION Inappropriate activation of the TLX1 (T-cell leukemia homeobox 1) gene by chromosomal translocation is a recurrent… (More)
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2010
2010
The homeobox gene TLX1 (for T-cell leukemia homeobox 1, previously known as HOX11) is inappropriately expressed in a major… (More)
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2002
2002
HOX11 is a transcription factor belonging to the homeodomain family that is essential for spleen development during embryogenesis… (More)
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1998
1998
The HOX11 homeobox gene was first identified through studies of the t(7;10) and t(10;14) chromosomal translocations of acute T… (More)
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1994
1994
The t(10;14) chromosomal translocation of T-cell acute lymphoblastic leukemia joins the T-cell receptor delta gene to a region… (More)
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1992
1992
Many nonrandom chromosome abnormalities have been associated with non-Hodgkin's lymphomas (NHL). Some of these are nonspecific… (More)
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Highly Cited
1991
Highly Cited
1991
Molecular cloning of the t(10;14)(q24;q11) recurrent breakpoint of T cell acute lymphoblastic leukemia has demonstrated a… (More)
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1990
1990
We cloned the t(10;14) recurrent translocation from CD3-negative T-cell acute lymphoblastic leukemia cells. The breakpoint at… (More)
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1990
1990
The t(10;14)(q24;q11) translocation is a non-random chromosome change seen in the leukemic cells of 5-10% of patients with T-cell… (More)
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1989
1989
The T-cell receptor (TCR) alpha/delta chain locus on chromosome 14q11 is nonrandomly involved in translocations and inversions in… (More)
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