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TLX1 gene

Known as: T-Cell Leukemia, Homeobox 1 Gene, HOMEOBOX 11, T-CELL LEUKEMIA 3 GENE 
This gene plays a role in transcriptional regulation and organogenesis. Translocations in the gene are associated with acute T-cell leukemia.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
The homeoprotein TLX1, which is essential to spleen organogenesis and oncogenic when aberrantly expressed in immature T cells… Expand
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2005
2005
Mice with disrupted mammalian PcG (Polycomb Group) genes commonly show skeletal transformation of anterior-posterior identities… Expand
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Highly Cited
2003
Highly Cited
2003
Mice in which all members of the Hox10 or Hox11 paralogous group are disrupted provide evidence that these Hox genes are involved… Expand
Highly Cited
2000
Highly Cited
2000
Formation of numerous internal organs involves reciprocal epithelial-mesenchymal signaling and subsequent patterning and growth… Expand
1999
1999
  • K. Patterson, Paul A. Krieg
  • Developmental dynamics : an official publication…
  • 1999
  • Corpus ID: 44263027
The mouse genome contains a small family of homeobox genes related to Hox11, but relatively little is known about the expression… Expand
1997
1997
We have used Southern blotting and fluorescence in situ hybridization (FISH) to define the breakpoints of a reciprocal… Expand
Highly Cited
1991
Highly Cited
1991
Molecular cloning of the t(10;14)(q24;q11) recurrent breakpoint of T cell acute lymphoblastic leukemia has demonstrated a… Expand
Highly Cited
1990
Highly Cited
1990
We cloned the t(10;14) recurrent translocation from CD3-negative T-cell acute lymphoblastic leukemia cells. The breakpoint at… Expand
1990
1990
The t(10;14)(q24;q11) translocation is a non‐random chromosome change seen in the leukemic cells of 5–10% of patients with T‐cell… Expand
Highly Cited
1989
Highly Cited
1989
The T-cell receptor (TCR) alpha/delta chain locus on chromosome 14q11 is nonrandomly involved in translocations and inversions in… Expand
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