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TLX1 gene

Known as: T-Cell Leukemia, Homeobox 1 Gene, HOMEOBOX 11, T-CELL LEUKEMIA 3 GENE 
This gene plays a role in transcriptional regulation and organogenesis. Translocations in the gene are associated with acute T-cell leukemia.
National Institutes of Health

Papers overview

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2017
2017
Gene fusions are observed in abnormal chromosomal rearrangements such as translocations in hematopoietic malignancies, especially… Expand
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2005
2005
Mice with disrupted mammalian PcG (Polycomb Group) genes commonly show skeletal transformation of anterior-posterior identities… Expand
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Highly Cited
2003
Highly Cited
2003
Mice in which all members of the Hox10 or Hox11 paralogous group are disrupted provide evidence that these Hox genes are involved… Expand
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Highly Cited
2000
Highly Cited
2000
Formation of numerous internal organs involves reciprocal epithelial-mesenchymal signaling and subsequent patterning and growth… Expand
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1999
1999
The mouse genome contains a small family of homeobox genes related to Hox11, but relatively little is known about the expression… Expand
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1997
1997
We have used Southern blotting and fluorescence in situ hybridization (FISH) to define the breakpoints of a reciprocal… Expand
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Highly Cited
1991
Highly Cited
1991
Molecular cloning of the t(10;14)(q24;q11) recurrent breakpoint of T cell acute lymphoblastic leukemia has demonstrated a… Expand
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1990
1990
We cloned the t(10;14) recurrent translocation from CD3-negative T-cell acute lymphoblastic leukemia cells. The breakpoint at… Expand
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1990
1990
The t(10;14)(q24;q11) translocation is a non-random chromosome change seen in the leukemic cells of 5-10% of patients with T-cell… Expand
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1989
1989
The T-cell receptor (TCR) alpha/delta chain locus on chromosome 14q11 is nonrandomly involved in translocations and inversions in… Expand
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