HOX11 protein

Known as: Homeo Box 11, Proto-Oncogene Tcl-3, T-Cell Leukemia 3 Protein 
T-cell leukemia homeobox protein 1 (330 aa, ~34 kDa) is encoded by the human TLX1 gene. This protein plays a role in the modulation of transcription.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1991-2013
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Highly Cited
2006
Highly Cited
2006
PURPOSE NOTCH signaling pathway is essential in T-cell development and NOTCH1 mutations are frequently present in T-cell acute… (More)
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2005
2005
The HOX11/TLX1 homeobox gene is aberrantly expressed in a subset of T-cell acute lymphoblastic leukemia (T-ALL). Here, we… (More)
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Highly Cited
2004
Highly Cited
2004
The activation of oncogenic transcription factors defines distinct molecular subsets of T-cell acute lymphoblastic leukaemia and… (More)
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2003
2003
HOX11 encodes a homeodomain protein that is aberrantly expressed in T-cell acute lymphoblastic leukemia as a consequence of the t… (More)
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2003
2003
Clonal genetic aberrations in tumour cells provide critical information for the development of new diagnostic and therapeutic… (More)
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1998
1998
HOX11, a divergent homeodomain-containing transcription factor, was isolated from the breakpoint of the nonrandom t(10;14)(q24… (More)
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1997
1997
The HOX11/TCL3 homeobox gene was identified at the breakpoint region in pediatric T-cell acute lymphoblastic leukemia harboring… (More)
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1994
1994
The t(10;14) chromosomal translocation of T-cell acute lymphoblastic leukemia joins the T-cell receptor delta gene to a region… (More)
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1993
1993
A translocation involving human chromosome 10, band q24, in a subset of T-cell acute leukemias disrupts a region surrounding the… (More)
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Highly Cited
1991
Highly Cited
1991
Molecular cloning of the t(10;14)(q24;q11) recurrent breakpoint of T cell acute lymphoblastic leukemia has demonstrated a… (More)
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