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Embryonic stem (ES) cells are pluripotent and of therapeutic potential in regenerative medicine. Understanding pluripotency at… Expand Embryonic stem (ES) cells undergo extended proliferation while remaining poised for multilineage differentiation. A unique… Expand Activation of multiple pathways is associated with cardiac hypertrophy and heart failure. Repression of antihypertrophic pathways… Expand ABI1, a protein phosphatase 2C, is a key component of signal transduction in Arabidopsis. It regulates diverse responses to the… Expand To identify genes targeted by the tobacco KNOX homeodomain protein, Nicotiana tabacum homeobox 15 (NTH15), we have generated an… Expand Diabetes is caused by a failure of the pancreas to produce insulin in amounts sufficient to meet the body's needs. A hallmark of… Expand We show that homothorax (hth) is required for the Hox genes to pattern the body of the fruit fly, Drosophila melanogaster. hth is… Expand THE KNOTTED class of plant genes encodes homeodomain proteins1,2. These genes have been found in all plant species where they… Expand Plasmodesmata are intercellular organelles in plants that establish cytoplasmic continuity between neighboring cells… Expand ASYMMETRIC divisions that produce two distinct cells play fundamental roles in generating different cell types during… Expand