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TLR5 wt Allele

Known as: SLE1, MGC126430, MGC126431 
Human TLR5 wild-type allele is located within 1q41-q42 and is approximately 33 kb in length. This allele, which encodes toll-like receptor 5 protein… 
National Institutes of Health

Related topics

Related topics

10 relations
1q41-q42Immune responseLigand BindingReceptor Signaling

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
TLR5 agonist entolimod reduces the adverse toxicity of TNF while preserving its antitumor effects
Tumor necrosis factor alpha (TNF) is capable of inducing regression of solid tumors. However, TNF released in response to Toll… 
2017
2017
Electrical and mechanical properties of molecular junctions and nano surfaces
The behaviour of two graphene based structures has been theoretically investigated and analysed by using one or more tools. This… 
2014
2014
Prior TLR5 induction in human T cells results in a transient potentiation of subsequent TCR-induced cytokine production.
2011
2011
Therapeutic potential of DCB-SLE1, an extract of a mixture of Chinese medicinal herbs, for severe lupus nephritis.
The pathogenesis of lupus nephritis is mainly attributable to a complex interaction between the innate and adaptive immune… 
2009
2009
The Lupus Susceptibility Locus Sle1 Breaches Peripheral B Cell Tolerance at the Antibody-Forming Cell and Germinal Center Checkpoints1
We have described a line of VH knock-in mice termed HKIR in which the transgenic Igh locus partially encodes “dual-reactive… 
2009
2009
TLR 5 stimulation is suf fi cient to trigger reactivation of latent HIV-1 provirus in T lymphoid cells and activate virus gene expression in central memory CD 4 + T cells
2007
2007
PI3K/AKT/mTOR hypersignaling in autoimmune lymphoproliferative disease engendered by the epistatic interplay of Sle1b and FASlpr.
Previous studies have demonstrated that the NZM2410/NZW 'z' allele of Sle1 on telomeric murine chromosome 1 led to… 
2006
2006
Toll-like receptor therapies compete to reduce side effects
An emerging class of highly specific immunomodulator drugs targeting toll-like receptors will be the focus of attention this… 
Highly Cited
2002
Highly Cited
2002
The Major Murine Systemic Lupus Erythematosus Susceptibility Locus Sle1 Results in Abnormal Functions of Both B and T Cells1
Sle1 is a major susceptibility locus in the NZM2410 murine model of systemic lupus erythematosus. When isolated on a C57BL/6… 
1990
1990
MELIOS: Status report of the U.S. Army's eyesafe laser rangefinder program
In 1980 the Army fielded the AN/GVS-5 Nd:YAG hand held laser rangefinder. The use and widespread deployment of the AN/GVS-5 was… 
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