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TLR2 protein, human

Known as: TIL4, Toll-Like Receptor 2, TLR2 
Toll-like receptor 2 (784 aa, ~90 kDa) is encoded by the human TLR2 gene. This protein is involved in signal transduction that modulates innate… 
National Institutes of Health

Related topics

Related topics

21 relations
Dendritic Cell PathwayImmunityIntegral Membrane ProteinsLeucine-Rich Repeat

Broader (1)

Toll-Like Receptor 2

Papers overview

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Highly Cited
2012
Highly Cited
2012
Probiotic Bifidobacterium breve Induces IL-10-Producing Tr1 Cells in the Colon
Specific intestinal microbiota has been shown to induce Foxp3+ regulatory T cell development. However, it remains unclear how… 
Highly Cited
2012
Highly Cited
2012
TLR2 Expression Is Regulated by MicroRNA miR-19 in Rheumatoid Fibroblast-like Synoviocytes
Resident cells, such as fibroblast-like synoviocytes (FLS), play a crucial role in rheumatoid arthritis (RA). They are implicated… 
Highly Cited
2010
Highly Cited
2010
Tlr2 is critical for diet‐induced metabolic syndrome in a murine model
Obesity and its associated comorbidities, termed metabolic syndrome, are increasingly prevalent, and they pose a serious threat… 
Review
2009
Review
2009
Chitin, Chitinases and Chitinase-like Proteins in Allergic Inflammation and Tissue Remodeling
Chitin, the second most abundant polysaccharide in nature after cellulose, consist exoskeleton of lower organisms such as fungi… 
Highly Cited
2007
Highly Cited
2007
Toll-like receptor 2 senses beta-cell death and contributes to the initiation of autoimmune diabetes.
Highly Cited
2006
Highly Cited
2006
Cutting Edge: TLR9 and TLR2 Signaling Together Account for MyD88-Dependent Control of Parasitemia in Trypanosoma cruzi Infection1
Activation of innate immune cells by Trypanosoma cruzi-derived molecules such as GPI anchors and DNA induces proinflammatory… 
Highly Cited
2005
Highly Cited
2005
Influence of exercise training and age on CD14+ cell-surface expression of toll-like receptor 2 and 4
Highly Cited
2005
Highly Cited
2005
The Tumor Suppressor Cylindromatosis (CYLD) Acts as a Negative Regulator for Toll-like Receptor 2 Signaling via Negative Cross-talk with TRAF6 and TRAF7*
Toll-like receptor 2 (TLR2) plays an important role in host defense against bacterial pathogens. Activation of TLR2 signaling not… 
Highly Cited
2004
Highly Cited
2004
Intact Gram-Negative Helicobacter pylori, Helicobacter felis, and Helicobacter hepaticus Bacteria Activate Innate Immunity via Toll-Like Receptor 2 but Not Toll-Like Receptor 4
ABSTRACT Molecular and genetic studies have demonstrated that members of the Toll-like receptor (TLR) family are critical innate… 
Highly Cited
2000
Highly Cited
2000
Toll-Like Receptor 4, But Not Toll-Like Receptor 2, Is a Signaling Receptor for Escherichia and Salmonella Lipopolysaccharides1
Two members of the mammalian Toll-like receptor (TLR) family, TLR2 and TLR4, have been implicated as receptors mediating cellular… 
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