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TLR2 gene

Known as: TIL4, toll like receptor 2, TLR2 
This gene plays a role in pathogen recognition and mediates the host response to gram-positive bacteria and yeast.
National Institutes of Health

Related topics

Related topics

8 relations
ImmunityLigand BindingPositive Regulation of ApoptosisReceptor Signaling

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Pre-Activation of Toll-Like Receptor 2 Enhances CD8+ T-Cell Responses and Accelerates Hepatitis B Virus Clearance in the Mouse Models
Toll-like receptors (TLRs) play a crucial role in activation of innate immunity, which is essential for inducing effective… 
Highly Cited
2012
Highly Cited
2012
Homozygosity for the toll-like receptor 2 R753Q single-nucleotide polymorphism is a risk factor for cytomegalovirus disease after liver transplantation.
Immunity against cytomegalovirus (CMV) is initiated after its recognition by Toll-like receptor 2 (TLR2). We assessed the… 
2012
2012
CONTRASTING PATTERNS OF DIVERSITY AND POPULATION DIFFERENTIATION AT THE INNATE IMMUNITY GENE TOLL‐LIKE RECEPTOR 2 (TLR2) IN TWO SYMPATRIC RODENT SPECIES
Comparing patterns of diversity and divergence between populations at immune genes and neutral markers can give insights into the… 
2011
2011
Titanium particles activate toll‐like receptor 4 independently of lipid rafts in RAW264.7 murine macrophages
Adherent pathogen‐associated molecular patterns (PAMPs) act through toll‐like receptor 2 (TLR2) and TLR4 to increase the… 
2010
2010
Involvement of TLR2 in Recognition of Acute Gammaherpesvirus-68 Infection
Background Toll-like receptors (TLRs) play a crucial role in the activation of innate immunity in response to many viruses. We… 
2010
2010
Combinatorial interference of toll-like receptor 2 and 4 synergistically stabilizes atherosclerotic plaque in apolipoprotein E-knockout mice
To test the hypothesis that combinatorial interference of toll‐like receptor 2 (TLR2) and TLR4 is superior to isolated… 
2009
2009
Rare TLR2 mutations reduce TLR2 receptor function and can increase atopy risk
Background:  Common genetic variations in toll‐like receptor 2 (TLR2), an innate pathogen recognition receptor, may influence the… 
2009
2009
A Network of Hydrogen Bonds on the Surface of TLR2 Controls Ligand Positioning and Cell Signaling*
TLR2 is a pattern recognition receptor that functions in association with TLR1 or TLR6 to mediate innate immune responses to a… 
2008
2008
The role of macrophage in the pathogenesis of chronic cyclosporine-induced nephropathy.
BACKGROUND Macrophages play diverse roles in tissue injury. We evaluated their role in cyclosporine (CsA)-induced renal injury by… 
2000
2000
CD3zeta and CD28 down-modulation on CD8 T cells during viral infection.
Down-modulation of CD3zeta expression on CD8 T lymphocytes occurs, independently of other T-cell receptor (TCR)-CD3 components… 
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