TLR1 wt Allele

Known as: Toll-Like Receptor 1 wt Allele, TIL. LPRS5, TIL._LPRS5 
Human TLR1 wild-type allele is located within 4p14 and is approximately 9 kb in length. This allele, which encodes toll-like receptor 1 protein… (More)
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
BACKGROUND Immune checkpoint inhibitors targeting programmed cell death 1 (PD1) or its ligand (PD-L1) showed activity in several… (More)
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Highly Cited
2012
Highly Cited
2012
PURPOSE To determine whether density and distribution of tumor-infiltrating lymphocytes (TILs; TIL grade) is an independent… (More)
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Highly Cited
2009
Highly Cited
2009
Tumor antigen-specific T cells are found within melanomas, yet tumors continue to grow. Although the tumor microenvironment is… (More)
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Highly Cited
2007
Highly Cited
2007
PURPOSE Immunosuppression, including that mediated by CD4(+)CD25(high)Foxp3(+) regulatory T cells (Treg), is a characteristic… (More)
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Highly Cited
2006
Highly Cited
2006
B7-H1 molecule increases the apoptosis of tumor-reactive T lymphocytes and reduces their immunogenicity. Breast cancer is the… (More)
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Highly Cited
2005
Highly Cited
2005
In a recent report, [Zhang et al. (2003) N. Engl. J. Med. 348, 203-213], the presence of CD3+ tumor-infiltrating lymphocytes… (More)
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Highly Cited
2003
Highly Cited
2003
The generation of T lymphocytes with specific reactivity against tumor antigens is a prerequisite for effective adoptive transfer… (More)
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Highly Cited
2002
Highly Cited
2002
The Toll-like receptor (TLR)9 is critical for the recognition of immunostimulatory CpG motifs but may cooperate with other TLRs… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Cells with deficient DNA mismatch repair develop microsatellite instability. Extensive microsatellite instability (MSI… (More)
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Highly Cited
2000
Highly Cited
2000
Members of the Toll-like receptor (TLR) family probably play a fundamental role in pathogen recognition and activation of innate… (More)
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