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TK2 gene

Known as: Thymidine Kinase 2, Mitochondrial Gene, SCA31, THYMIDINE KINASE, MITOCHONDRIAL 
This gene plays a role in mitochondrial DNA synthesis in non-replicating cells.
National Institutes of Health

Related topics

Related topics

3 relations
DNA ReplicationPhosphorylationTK2 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
[Clinical features and MRI findings in spinocerebellar ataxia type 31 (SCA31) comparing with spinocerebellar ataxia type 6 (SCA6)].
Since the discovery of spinocerebellar ataxia type 31 (SCA31) gene, we identified 6 patients whose SCA type had been unkown for a… 
2013
2013
Distinctive features of degenerating Purkinje cells in spinocerebellar ataxia type 31
Spinocerebellar ataxia type 31 (SCA31) is an autosomal dominant form of pure cerebellar ataxia that is caused by a disease… 
2011
2011
Two dominantly inherited ataxias linked to chromosome 16q22.1: SCA4 and SCA31 are not allelic
Autosomal dominant spinocerebellar ataxias (SCAs) are heterogeneous neurological disorders characterised by cerebellar… 
2011
2011
Comparisons of acoustic function in SCA31 and other forms of ataxias
Abstract Objective: To investigate whether acoustic impairment can be one of the characteristic extracerebellar symptoms in… 
2008
2008
5-Bromovinyl 2′-Deoxyuridine Phosphorylation by Mitochondrial and Cytosolic Thymidine Kinase (TK2 and TK1) and Its Use in Selective Measurement of TK2 Activity in Crude Extracts
Mitochondrial thymidine kinase (TK2) is responsible for phosphorylation of thymidine and deoxycytidine and plays a crucial role… 
2000
2000
Expression of human mitochondrial thymidine kinase in Escherichia coli: correlation between the enzymatic activity of pyrimidine nucleoside analogues and their inhibitory effect on bacterial growth.
Highly Cited
1992
Highly Cited
1992
Thymidine and 3'-azido-3'-deoxythymidine metabolism in human peripheral blood lymphocytes and monocyte-derived macrophages. A study of both anabolic and catabolic pathways.
1991
1991
Deoxynucleoside phosphorylating enzymes in monkey and human tissues show great similarities, while mouse deoxycytidine kinase has a different substrate specificity.
1987
1987
A novel HLA class II alloantigen detected by an alloantiserum TK2.
1985
1985
Detection of bone marrow involvement by neuroblastoma: Comparison of two cytological methods
In order to improve the assessment of bone marrow (BM) involvement by neuroblastoma, a study has been designated on aspirated… 
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