TINF2 protein, human

Known as: TRF1-interacting nuclear factor 2 protein, human, TRF1-Interacting Nuclear Protein 2, TINF2 
TERF1-interacting nuclear factor 2 (451 aa, ~50 kDa) is encoded by the human TINF2 gene. This protein plays a role in both the regulation of telomere… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1999-2017
051019992017

Papers overview

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Highly Cited
2010
Highly Cited
2010
Human telomeres bind shelterin, the six-subunit protein complex that protects chromosome ends from the DNA damage response and… (More)
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Highly Cited
2008
Highly Cited
2008
Mammalian telomeres are protected by a six-protein complex: shelterin. Shelterin contains two closely related proteins (TRF1 and… (More)
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Highly Cited
2006
Highly Cited
2006
Mammalian telomeric proteins function through dynamic interactions with each other and telomere DNA. We previously reported the… (More)
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Highly Cited
2004
Highly Cited
2004
In mammalian cells, telomere-binding proteins TRF1 and TRF2 play crucial roles in telomere biology. They interact with several… (More)
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Highly Cited
2004
Highly Cited
2004
Telomere maintenance has been implicated in cancer and ageing, and requires cooperation between a multitude of telomeric factors… (More)
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Highly Cited
2004
Highly Cited
2004
The human telomere binding protein hPot1 binds to the most distal single-stranded extension of telomeric DNA in vitro, and… (More)
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Highly Cited
2004
Highly Cited
2004
Human telomere length is controlled by a negative feedback loop based on the binding of TRF1 to double-stranded telomeric DNA… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Human telomeres are coated by the telomere repeat binding proteins TRF1 and TRF2, which are believed to function… (More)
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Highly Cited
2004
Highly Cited
2004
Telomeres are protective structures at chromosome ends and are crucial for genomic stability. Mammalian TRF1 and TRF2 bind the… (More)
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Highly Cited
1999
Highly Cited
1999
Telomeres are DNA-protein structures that cap linear chromosomes and are essential for maintaining genomic stability and cell… (More)
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