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TINF2 protein, human

Known as: TRF1-interacting nuclear factor 2 protein, human, TRF1-Interacting Nuclear Protein 2, TINF2 
TERF1-interacting nuclear factor 2 (451 aa, ~50 kDa) is encoded by the human TINF2 gene. This protein plays a role in both the regulation of telomere… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
In vertebrates, two Scc3 homologues control sister chromatid cohesion of distinct chromosomal regions. 
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Highly Cited
2006
Highly Cited
2006
Mammalian telomeric proteins function through dynamic interactions with each other and telomere DNA. We previously reported the… Expand
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Review
2005
Review
2005
Added by telomerase, arrays of TTAGGG repeats specify the ends of human chromosomes. A complex formed by six telomere-specific… Expand
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Human telomeres are coated by the telomere repeat binding proteins TRF1 and TRF2, which are believed to function… Expand
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Highly Cited
2004
Highly Cited
2004
Telomere maintenance has been implicated in cancer and ageing, and requires cooperation between a multitude of telomeric factors… Expand
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Highly Cited
2004
Highly Cited
2004
Telomere length in humans is partly controlled by a feedback mechanism in which telomere elongation by telomerase is limited by… Expand
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Highly Cited
2004
Highly Cited
2004
Human telomeres contain two related telomeric DNA-binding proteins, TRF1 and TRF2. The TRF1 complex contains the TRF1 interacting… Expand
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Highly Cited
2004
Highly Cited
2004
Telomeres are protective structures at chromosome ends and are crucial for genomic stability. Mammalian TRF1 and TRF2 bind the… Expand
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Highly Cited
2000
Highly Cited
2000
It has been puzzling that mammalian telomeric proteins, including TRF1, TRF2, tankyrase, and TIN2 have no recognized orthologs in… Expand
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Highly Cited
1999
Highly Cited
1999
Telomeres are DNA-protein structures that cap linear chromosomes and are essential for maintaining genomic stability and cell… Expand
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