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TINF2 protein, human

Known as: TRF1-interacting nuclear factor 2 protein, human, TRF1-Interacting Nuclear Protein 2, TINF2 
TERF1-interacting nuclear factor 2 (451 aa, ~50 kDa) is encoded by the human TINF2 gene. This protein plays a role in both the regulation of telomere… Expand
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
We have performed first-principles evolutionary searches for stable Ti-N compounds and have found, in addition to the well-known… Expand
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Highly Cited
2011
Highly Cited
2011
Human telomere function is mediated by shelterin, a six-subunit complex that is required for telomere replication, protection… Expand
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Highly Cited
2007
Highly Cited
2007
Previous studies in human cells indicate that sister telomeres have distinct requirements for their separation at mitosis. In… Expand
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Highly Cited
2006
Highly Cited
2006
Mammalian telomeric proteins function through dynamic interactions with each other and telomere DNA. We previously reported the… Expand
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Review
2005
Review
2005
Added by telomerase, arrays of TTAGGG repeats specify the ends of human chromosomes. A complex formed by six telomere-specific… Expand
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Highly Cited
2004
Highly Cited
2004
Telomere maintenance has been implicated in cancer and ageing, and requires cooperation between a multitude of telomeric factors… Expand
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Highly Cited
2004
Highly Cited
2004
Human telomeres contain two related telomeric DNA-binding proteins, TRF1 and TRF2. The TRF1 complex contains the TRF1 interacting… Expand
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Highly Cited
2001
Highly Cited
2001
Telomeric repeat binding factor 1 (TRF1) and 2 (TRF2) may play key roles in the maintenance of telomere function. TRF1 negatively… Expand
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Highly Cited
2000
Highly Cited
2000
It has been puzzling that mammalian telomeric proteins, including TRF1, TRF2, tankyrase, and TIN2 have no recognized orthologs in… Expand
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Highly Cited
1999
Highly Cited
1999
Telomeres are DNA-protein structures that cap linear chromosomes and are essential for maintaining genomic stability and cell… Expand
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