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THRSP gene

Known as: Thyroid Hormone Responsive Gene, SPOT14, SPOT14 homolog (rat) 
This gene plays a role in the modulation of lipid biosynthesis.
National Institutes of Health

Related topics

Related topics

4 relations
AdipogenesisLipid MetabolismTHRSP protein, humanThrsp protein, rat

Papers overview

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Highly Cited
2013
Highly Cited
2013
Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis
Mechanisms controlling the proliferative activity of neural stem and progenitor cells (NSPCs) have a pivotal role to ensure life… 
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Highly Cited
2012
Highly Cited
2012
Developmental triclosan exposure decreases maternal, fetal, and early neonatal thyroxine: a dynamic and kinetic evaluation of a putative mode-of-action.
This work tests the mode-of-action (MOA) hypothesis that maternal and developmental triclosan (TCS) exposure decreases… 
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Highly Cited
2011
Highly Cited
2011
Detection of thyroid hormone receptor disruptors by a novel stable in vitro reporter gene assay.
A stable luciferase reporter gene assay was developed based on the thyroid hormone responsive rat pituitary tumor GH3 cell line… 
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Highly Cited
2009
Highly Cited
2009
Expression of enzymes and key regulators of lipid synthesis is upregulated in adipose tissue during CLA-induced milk fat depression in dairy cows.
Milk fat depression (MFD) is a naturally occurring condition in dairy cows where milk fat synthesis is inhibited by intermediates… 
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Highly Cited
2009
Highly Cited
2009
Peroxisome proliferator-activated receptor-gamma activation and long-chain fatty acids alter lipogenic gene networks in bovine mammary epithelial cells to various extents.
Several long-chain fatty acids (LCFA) are natural ligands of nonruminant peroxisome proliferator-activated receptor-gamma (PPARG… 
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Highly Cited
2006
Highly Cited
2006
SREBP1 and thyroid hormone responsive spot 14 (S14) are involved in the regulation of bovine mammary lipid synthesis during diet-induced milk fat depression and treatment with CLA.
Milk fat synthesis in dairy cows can be inhibited by unique fatty acid intermediates that are produced during rumen… 
Highly Cited
1993
Highly Cited
1993
The glycoinositol phospholipids of Leishmania mexicana promastigotes. Evidence for the presence of three distinct pathways of glycolipid biosynthesis.
Most macromolecules at the cell surface of parasitic protozoa of the genus Leishmania, including the major surface glycoproteins… 
Highly Cited
1992
Highly Cited
1992
H‐2RIIBP (RXR beta) heterodimerization provides a mechanism for combinatorial diversity in the regulation of retinoic acid and thyroid hormone responsive genes.
H‐2RIIBP (RXR beta) is a member of the nuclear hormone receptor superfamily that activates transcription of MHC class I genes in… 
Highly Cited
1988
Highly Cited
1988
c-erbA protooncogenes mediate thyroid hormone-dependent and independent regulation of the rat growth hormone and prolactin genes.
Regulation of gene expression by the thyroid hormones is thought to be mediated by a nuclear-associated receptor found in a wide… 
Highly Cited
1986
Highly Cited
1986
Thyroid hormone regulation of the transfected rat growth hormone promoter.
A region of the rat growth hormone gene and 5' flanking DNA has been identified which promotes accurate, thyroid hormone… 
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