THRSP gene

Known as: Thyroid Hormone Responsive Gene, SPOT14, SPOT14 homolog (rat) 
This gene plays a role in the modulation of lipid biosynthesis.
National Institutes of Health

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4 relations
AdipogenesisLipid MetabolismTHRSP protein, humanThrsp protein, rat

Papers overview

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2011
2011
Detection of thyroid hormone receptor disruptors by a novel stable in vitro reporter gene assay.
A stable luciferase reporter gene assay was developed based on the thyroid hormone responsive rat pituitary tumor GH3 cell line… (More)
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2010
2010
Modular Insulators: Genome Wide Search for Composite CTCF/Thyroid Hormone Receptor Binding Sites
The conserved 11 zinc-finger protein CTCF is involved in several transcriptional mechanisms, including insulation and enhancer… (More)
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Highly Cited
2009
Highly Cited
2009
Gene expression patterns during intramuscular fat development in cattle.
Deposition of intramuscular fat, or "marbling," in beef cattle contributes significantly to meat quality variables, including… (More)
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Highly Cited
2009
Highly Cited
2009
Peroxisome proliferator-activated receptor-gamma activation and long-chain fatty acids alter lipogenic gene networks in bovine mammary epithelial cells to various extents.
Several long-chain fatty acids (LCFA) are natural ligands of nonruminant peroxisome proliferator-activated receptor-gamma (PPARG… (More)
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2009
2009
Conjugated linoleic acid (CLA) inhibits expression of the Spot 14 (THRSP) and fatty acid synthase genes and impairs the growth of human breast cancer and liposarcoma cells.
Spot 14 (THRSP, S14) is a nuclear protein involved in the regulation of genes required for fatty acid synthesis in normal and… (More)
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2005
2005
Modulation at a cellular level of the thyroid hormone receptor-mediated gene expression by 1,2,5,6,9,10-hexabromocyclododecane (HBCD), 4,4'-diiodobiphenyl (DIB), and nitrofen (NIP).
Previously, we demonstrated that some endocrine disrupting chemicals affected thyroid hormone receptor (TR)-mediated gene… (More)
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2005
2005
Expression of “Spot 14” (THRSP) predicts disease free survival in invasive breast cancer: immunohistochemical analysis of a new molecular marker
Most breast cancers are “lipogenic”, defined by high fatty acid synthase (FAS) content and dependence on fatty acid synthesis for… (More)
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2005
2005
Thyroid hormone receptors alpha1 and beta1 are downregulated in the post-infarcted rat heart: consequences on the response to ischaemia-reperfusion.
There is accumulating evidence that thyroid hormone metabolism is altered after myocardial infarction (AMI) but its physiological… (More)
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2004
2004
CRIKEY - a temporal planner looking at the integration of scheduling and planning
For many temporal planning domains, the planning and scheduling problems are not tightly coupled and so can be solved separately… (More)
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1993
1993
Distinct behavior of cardiac myosin heavy chain gene constructs in vivo. Discordance with in vitro results.
Transcriptional thyroid hormone responsiveness of the cardiac alpha-myosin heavy chain (alpha-MHC) gene has been demonstrated in… (More)
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