THERATOPE

Cancer vaccines have demonstrated that they can stimulate antibody and cell-mediated immune responses against tumor-associated… Expand

2547 Background: Theratope is an investigational therapeutic cancer vaccine consisting of a synthetic form of STn conjugated to… Expand

Mucin-1 (MUC-1) is a high-molecular-weight glycoprotein rich in serine and threonine residues that are O-glycosylated. Expression… Expand

The success of high-dose chemotherapy followed by autologous stem-cell rescue as treatment for breast and ovarian cancer is… Expand

The development of active specific immunotherapy depends on the identification of altered cancer cell-specific molecules or… Expand

Active specific immunotherapy (ASI) is a promising approach to treating cancer. Numerous studies in the laboratory have… Expand

The purpose of this study was to evaluate the toxicity and potential efficacy of administering the THERATOPE® STn-KLH cancer… Expand

Active specific immunotherapy, the use of 'vaccines' to stimulate therapeutic tumor antigen-specific immune responses, holds… Expand

THERATOPE (Biomira Inc., Edmonton, AB, Canada) STn-KLH cancer vaccine induces strong antibody titers against both the synthetic… Expand

Abstract Patients with metastatic breast, colorectal or ovarian cancers received active specific immunotherapy (ASI) with… Expand