THERATOPE

Changes in the composition of glycans added to glycoproteins and glycolipids are characteristic of the change to malignancy… (More)

Cancer vaccines have demonstrated that they can stimulate antibody and cell-mediated immune responses against tumor-associated… (More)

2547 Background: Theratope is an investigational therapeutic cancer vaccine consisting of a synthetic form of STn conjugated to… (More)

The success of high-dose chemotherapy followed by autologous stem-cell rescue as treatment for breast and ovarian cancer is… (More)

Biomira is developing a therapeutic cancer vaccine [THERATOPE] for treatment of breast and other cancers. This profile has been… (More)

The development of active specific immunotherapy depends on the identification of altered cancer cell-specific molecules or… (More)

Mucin-1 (MUC-1) is a high-molecular-weight glycoprotein rich in serine and threonine residues that are O-glycosylated. Expression… (More)

Active specific immunotherapy (ASI) is a promising approach to treating cancer. Numerous studies in the laboratory have… (More)

Active specific immunotherapy, the use of 'vaccines' to stimulate therapeutic tumor antigen-specific immune responses, holds… (More)

THERATOPE (Biomira Inc., Edmonton, AB, Canada) STn-KLH cancer vaccine induces strong antibody titers against both the synthetic… (More)