sialyl-Tn antigen-keyhole-limpet hemocyanin conjugate

Known as: STn-KLH Vaccine, Theratope siayl-Tn-KLH vaccine, Sialyl Tn-KLH Vaccine 
A vaccine containing a pancarcinoma carbohydrate antigen conjugated with keyhole limpet hemocyanin (KLH), with potential antineoplastic activity… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1993-2017
01219932017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
PURPOSE This double-blind, randomized, phase III clinical trial evaluated time to progression (TTP) and overall survival in women… (More)
Is this relevant?
2000
2000
The purpose of this study was to evaluate the toxicity and potential efficacy of administering the THERATOPE® STn-KLH cancer… (More)
  • table 1
  • table 2
  • table 3
  • table 4
  • figure 1
Is this relevant?
1999
1999
Sialyl-Tn (STn) is an O-serine- or O-threonine-linked disaccharide [NeuAcα(2→6)GalNAcα- O-Ser/Thr) expressed on mucins of most… (More)
  • figure 1
  • table 2
  • table 1
  • table 3
  • table 4
Is this relevant?
1999
1999
Seven ovarian and 33 breast high-risk stage II/III and stage IV cancer patients received high-dose chemotherapy followed by stem… (More)
Is this relevant?
1998
1998
STn (NeuAcα2→6GalNAcα-O-Ser/Thr) is a carbohydrate epitope overexpressed in various human carcinomas. Clinical trials are… (More)
  • figure 1
  • table 1
  • table 2
  • table 3
Is this relevant?
1996
1996
THERATOPE (Biomira Inc., Edmonton, AB, Canada) STn-KLH cancer vaccine induces strong antibody titers against both the synthetic… (More)
Is this relevant?
1996
1996
The humoral immune response of 85 metastatic breast, ovarian, and colorectal cancer patients was analyzed after immunization with… (More)
Is this relevant?
1996
1996
Studies in animal models of mouse mammary carcinoma have shown that ovine submaxillary mucin, which carries multiple sialyl-Tn… (More)
  • figure 1
  • table I
  • figure 2
Is this relevant?
1993
1993
We have synthesized various formulations that have potential for active specific immunotherapy (ASI) of human cancers. Sialyl-Tn… (More)
  • table 1
  • table 3
  • table 2
  • figure 2
  • table 4
Is this relevant?
1993
1993
We generated a synthetic epitope, NANA alpha(2-6) GalNAc alpha-O-Crotyl (STn-crotyl), designed to "mimic" the natural O-linked… (More)
Is this relevant?