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THBS2 gene

Known as: THBS2, thrombospondin 2, TSP2 
This gene is involved in the mediation of both intercellular and cell-matrix interactions. It also plays a role in the inhibition of angiogenesis.
National Institutes of Health

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Related topics

5 relations
Angiogenic ProcessCell-Cell Adhesion ProcessCell-Matrix Junctionthrombospondin 2

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THBS2 wt Allele

Papers overview

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2019
2019
MicroRNA‐20a regulates cell proliferation, apoptosis and autophagy by targeting thrombospondin 2 in cervical cancer
2017
2017
Macroglia-derived thrombospondin 2 regulates alterations of presynaptic proteins of retinal neurons following elevated hydrostatic pressure
Many studies on retinal injury and repair following elevated intraocular pressure suggest that the survival ratio of retinal… 
2016
2016
Associations of THBS2 and THBS4 polymorphisms to gastric cancer in a Southeast Chinese population.
2015
2015
Complex Brain Malformations Associated with Chromosome 6q27 Gain that Includes THBS2, Which Encodes Thrombospondin 2, an Astrocyte-Derived Protein of the Extracellular Matrix
This case describes the autopsy findings of a 2-month-old male infant with extensive and severe developmental brain abnormalities… 
2011
2011
Circulating levels of the anti‐angiogenic thrombospondin 2 are elevated in pre‐eclampsia
An imbalance of maternal circulating pro‐ and anti‐angiogenic factors may play a role in the pathogenesis of pre‐eclampsia… 
Highly Cited
2006
Highly Cited
2006
Comparative integromics on Angiopoietin family members.
Angiopoietin-1 (ANGPT1), Angiopoietin-4 (ANGPT4), VEGF, FGF2, FGF4, HGF, Ephrin, IL8 and CXCL12 (SFD1) are pro-angiogenic factors… 
2005
2005
Differential expression of angioregulatory matricellular proteins in posterior uveal melanoma
Metastases from uveal melanoma, the most common primary malignant eye tumour in adults, develop solely via their vascular bed due… 
Highly Cited
2003
Highly Cited
2003
Frequent HOXA11 and THBS2 promoter methylation, and a methylator phenotype in endometrial adenocarcinoma.
PURPOSE This study was designed to determine whether there is a methylator phenotype in stage I and II endometrioid endometrial… 
1998
1998
Myb-dependent Regulation of Thrombospondin 2 Expression
The nuclear transcription factor c-Myb, which is highly expressed in hematopoietic cells, has been shown to be functional in NIH… 
1993
1993
Sequence and characterization of the complete human thrombospondin 2 cDNA: potential regulatory role for the 3' untranslated region.
We report the remainder of the cDNA sequence for human thrombospondin 2 (hTSP2) including the 5' and 3' untranslated regions. The… 
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