thrombospondin 2

Known as: THBS2, Thrombospondin-2, TSP2 
Thrombospondin-2 (1172 aa, ~130 kDa) is encoded by the human THBS2 gene. This protein plays a role in both cell-cell and cell-matrix interactions.
National Institutes of Health

Papers overview

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Review
2012
Review
2012
Thrombospondins TSP-1 and TSP-2 are potent endogenous inhibitors of angiogenesis. They inhibit angiogenesis through direct… (More)
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Highly Cited
2006
Highly Cited
2006
PURPOSE Bevacizumab is a monoclonal antibody to vascular endothelial growth factor-A (VEGF). In the pivotal trial in metastatic… (More)
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Highly Cited
2006
Highly Cited
2006
Schistosomes are blood-dwelling flukes that infect 200 million people worldwide and are responsible for hundreds of thousands of… (More)
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Highly Cited
2004
Highly Cited
2004
Cardiac hypertrophy can lead to heart failure (HF), but it is unpredictable which hypertrophied myocardium will progress to HF… (More)
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Highly Cited
2001
Highly Cited
2001
We have recently shown that the adhesive defect observed in dermal fibroblasts derived from thrombospondin 2 (TSP2)-null mice… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Recent advances in high-throughput genomics technology have expanded our ability to catalogue allelic variants in… (More)
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Highly Cited
2001
Highly Cited
2001
The angiogenic switch during tumorigenesis is thought to be induced by a change in the balance of pro- angiogenic and anti… (More)
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Highly Cited
2000
Highly Cited
2000
Thrombospondins are thought to function as inhibitors of angiogenesis. However, the mechanism(s) of this activity is not well… (More)
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Highly Cited
1999
Highly Cited
1999
Recent evidence suggests a potential role for thrombospondin-2 (TSP-2), a matricellular glycoprotein, in the regulation of… (More)
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Highly Cited
1995
Highly Cited
1995
To assess the ability of proteins of the thrombospondin family to inhibit angiogenesis, recombinant murine thrombospondin-2… (More)
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