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thrombospondin 2

Known as: THBS2, Thrombospondin-2, TSP2 
Thrombospondin-2 (1172 aa, ~130 kDa) is encoded by the human THBS2 gene. This protein plays a role in both cell-cell and cell-matrix interactions.
National Institutes of Health

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Related topics

15 relations
Angiogenesis Inhibitory ProteinAngiogenic ProcessBinding ProteinsBlood Platelets

Broader (1)

Thrombospondins

Papers overview

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2016
2016
Associations of THBS2 and THBS4 polymorphisms to gastric cancer in a Southeast Chinese population.
2010
2010
Alteration of thrombospondin-1 and -2 in rat brains following experimental intracerebral hemorrhage. Laboratory investigation.
OBJECT Spontaneous intracerebral hemorrhage (ICH) is among the most intractable forms of stroke. Angiogenesis, an orchestrated… 
Highly Cited
2007
Highly Cited
2007
Angiogenic response caused by oncolytic herpes simplex virus-induced reduced thrombospondin expression can be prevented by specific viral mutations or by administering a thrombospondin-derived…
Wild-type (WT) herpes simplex virus (HSV) causes some pathology, such as ocular keratitis, by increasing infected tissue… 
Highly Cited
2006
Highly Cited
2006
Infrared exposure induces an angiogenic switch in human skin that is partially mediated by heat
Background  Angiogenesis plays an important role in physiological and pathological conditions of the skin. Although acute… 
2004
2004
Thrombospondin 2 Deficiency in Pregnant Mice Results in Premature Softening of the Uterine Cervix1
Abstract The gradual disorganization of collagen fibers in the stromal connective tissue of the uterine cervix is characteristic… 
Highly Cited
2002
Highly Cited
2002
Increased and prolonged inflammation and angiogenesis in delayed-type hypersensitivity reactions elicited in the skin of thrombospondin-2--deficient mice.
Angiogenesis and enhanced microvascular permeability are hallmarks of a large number of inflammatory diseases. Although up… 
Highly Cited
2001
Highly Cited
2001
Thrombospondin-1 and -2 messenger RNA expression in invasive cervical cancer: correlation with angiogenesis and prognosis.
PURPOSE TSP association with clinicopathological features, including microvessel count, regarding prognostic significance was… 
Highly Cited
1998
Highly Cited
1998
Thrombospondin 2 gene expression is correlated with decreased vascularity in non-small cell lung cancer.
Stromal vascularity is thought to be a major factor involved in the progression of carcinoma. However, the crucial mechanisms of… 
1995
1995
Thrombospondins selectively activate one of the two latent forms of transforming growth factor-beta present in adrenocortical cell-conditioned medium.
Transforming growth factor-beta (TGF beta) has been shown previously to be a potent inhibitor of bovine adrenocortical cell… 
1994
1994
Modulation of thrombospondin expression during differentiation of embryonal carcinoma cells
The thrombospondins (TSPs) are a family of extracellular glycoproteins that display distinct patterns of temporal and spatial… 
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