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TGFBR2 gene

Known as: TRANSFORMING GROWTH FACTOR-BETA RECEPTOR, TYPE II, Transforming Growth Factor, Beta Receptor II (70/80kDa) Gene, transforming growth factor beta receptor II 
This gene plays a role in cellular proliferation and mitogenic responses.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Loeys-Dietz syndrome (LDS) is an autosomal dominant connective tissue disorder characterized mainly by cardiovascular… Expand
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Review
2014
Review
2014
Disrupted transforming growth factor- β (TGF-β) signaling is involved in the development of various types of cancer and the TGF… Expand
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2014
2014
It has been suggested that environmental and genetic factors may affect the individual’s susceptibility to cancer (Derynck et al… Expand
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2014
2014
BackgroundMicroRNAs (miRNAs) have been reported to play crucial roles in regulating a variety of genes pivotal for tumor… Expand
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2010
2010
PURPOSE Transforming growth factor beta receptors II gene (TGFBR2) mutations associated with Marfan syndrome and Marfan… Expand
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Highly Cited
2009
Highly Cited
2009
BACKGROUND TGFBR2 mutations were recognized recently among patients with a Marfan-like phenotype. The associated clinical and… Expand
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2008
2008
The implication of mutations in the TGFBR2 gene, known to be involved in cancers, in Marfan syndrome (MFS) and later in Loeys… Expand
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2006
2006
TGF-β-receptor 2 (TGFBR2) gene defects have been recently associated with Marfan syndrome (MFS) with prominent cardio-skeletal… Expand
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Highly Cited
2004
Highly Cited
2004
Marfan syndrome is an extracellular matrix disorder with cardinal manifestations in the eye, skeleton and cardiovascular systems… Expand
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Highly Cited
1998
Highly Cited
1998
Transforming growth factor beta (TGF-beta) is an extracellular ligand that binds to a heterodimeric receptor, initiating signals… Expand
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