TGFBR2 gene

Known as: TRANSFORMING GROWTH FACTOR-BETA RECEPTOR, TYPE II, Transforming Growth Factor, Beta Receptor II (70/80kDa) Gene, transforming growth factor beta receptor II 
This gene plays a role in cellular proliferation and mitogenic responses.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1994-2017
051019942017

Papers overview

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2014
2014
Prostate cancer cells escape growth inhibition from transforming growth factor β (TGFβ) by downregulating TGFβ receptors. However… (More)
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2011
2011
Mutations in the genes encoding transforming growth factor β receptors 1 and 2 (TGFBR1 and TGFBR2) have recently been associated… (More)
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2010
2010
PURPOSE Transforming growth factor beta (TGFbeta) is a pleiotropic cytokine that affects tumor growth, metastasis, stroma, and… (More)
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2009
2009
BACKGROUND TGFBR2 mutations were recognized recently among patients with a Marfan-like phenotype. The associated clinical and… (More)
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Highly Cited
2009
Highly Cited
2009
Colorectal cancer is one of the most common cancers worldwide. We tested the hypothesis that differences in the expression of… (More)
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2008
2008
The implication of mutations in the TGFBR2 gene, known to be involved in cancers, in Marfan syndrome (MFS) and later in Loeys… (More)
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2006
2006
TGF-β-receptor 2 (TGFBR2) gene defects have been recently associated with Marfan syndrome (MFS) with prominent cardio-skeletal… (More)
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2005
2005
Transgenic and gene knock-out studies demonstrated that the mouse Forkhead Box m1 (Foxm1 or Foxm1b) transcription factor… (More)
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2004
2004
PURPOSE The role of transforming growth factor beta (TGF-beta) in breast cancer is ambiguous; it can display both tumor… (More)
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1997
1997
Disruption of the DNA mismatch repair system, characterized by microsatellite instability (MI), plays an important role in the… (More)
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