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TGFBR2 wt Allele

Known as: HNPCC6, TGFBR2, Transforming Growth Factor, Beta Receptor II (70/80kDa) wt Allele 
Human TGFBR2 wild-type allele is located within 3p22 and is approximately 88 kb in length. This allele, which encodes TGF-beta receptor type-2… 
National Institutes of Health

Related topics

Related topics

18 relations
3p22ALK PathwayCTCF PathwayCell Proliferation

Broader (1)

TGFBR2 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Circular RNA FOXO3 Suppresses Bladder Cancer Progression and Metastasis by Regulating MiR-9-5p/TGFBR2
Background Increasing evidence indicates that the dysregulation of circular RNAs (circRNAs) plays important roles in tumor… 
2019
2019
A TGFBR2/SMAD2/DNMT1/miR-145 negative regulatory loop is responsible for LPS-induced sepsis.
Highly Cited
2019
Highly Cited
2019
Absence of TGFβ signaling in retinal microglia induces retinal degeneration and exacerbates choroidal neovascularization
Constitutive TGFβ signaling is important in maintaining retinal neurons and blood vessels and is a factor contributing to the… 
2017
2017
Epigenetically-Regulated MicroRNA-9-5p Suppresses the Activation of Hepatic Stellate Cells via TGFBR1 and TGFBR2
Background/Aims: Recently, microRNAs (miRNAs) have been demonstrated to act as regulators of activation of hepatic stellate cells… 
Highly Cited
2017
Highly Cited
2017
Differential Expression of miR-93 and miR-21 in Granulosa Cells and Follicular Fluid of Polycystic Ovary Syndrome Associating with Different Phenotypes
The heterogeneous and multifactorial essence of polycystic ovary syndrome (PCOS) renders a remarkable significance to microRNAs… 
2017
2017
Transforming growth factor-β signaling pathway-associated genes SMAD2 and TGFBR2 are implicated in metabolic syndrome in a Taiwanese population
The transforming growth factor-β (TGF-β) signaling pathway and its relevant genes have been correlated with an increased risk of… 
Highly Cited
2014
Highly Cited
2014
Polymorphisms in Inflammatory and Immune Response Genes Associated with Cerebral Cavernous Malformation Type 1 Severity
Background: Familial cerebral cavernous malformation type 1 (CCM1) is an autosomal dominant disease caused by mutations in the… 
Highly Cited
2013
Highly Cited
2013
Inactivation of Tgfbr2 in Osterix-Cre expressing dental mesenchyme disrupts molar root formation.
2009
2009
Tgfbr2 is required for development of the skull vault.
Highly Cited
2001
Highly Cited
2001
Inhibiting mutations in the transforming growth factor beta type 2 receptor in recurrent human breast cancer.
Members of the transforming growth factor beta (TGF-beta) family are potent inhibitors of the growth of many epithelial cell… 
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