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TGFB2 gene

Known as: transforming growth factor beta 2, prepro-transforming growth factor beta-2, Transforming Growth Factor, Beta 2 Gene 
This gene is involved in suppressing the growth of T cells.
National Institutes of Health

Related topics

Related topics

9 relations
Cell Differentiation processCell Proliferation Regulatory ProcessHomo sapiensInhibition of Cell Proliferation

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TGFB2 wt Allele

Papers overview

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2017
2017
First-in-human phase I study of ISTH0036, an antisense oligonucleotide selectively targeting transforming growth factor beta 2 (TGF-β2), in subjects with open-angle glaucoma undergoing glaucoma…
Purpose To evaluate the safety and tolerability of intravitreal ISTH0036, an antisense oligonucleotide selectively targeting… 
Highly Cited
2012
Highly Cited
2012
TGFB2 loss of function mutations cause familial thoracic aortic aneurysms and acute aortic dissections associated with mild systemic features of the Marfan syndrome
A predisposition for thoracic aortic aneurysms leading to acute aortic dissections can be inherited in families in an autosomal… 
2002
2002
Genetic susceptibility to keloid disease and transforming growth factor beta 2 polymorphisms.
Keloid disease (KD) is a benign fibroproliferative scarring condition of unknown aetiopathogenesis. There is a familial… 
Review
2001
Review
2001
The effect of pasteurization on transforming growth factor alpha and transforming growth factor beta 2 concentrations in human milk.
Transforming growth factor alpha (TGF-alpha) and beta 2 (TGF-beta2) are present in human milk and are involved in growth… 
Highly Cited
1997
Highly Cited
1997
Genetic linkage analysis of growth factor loci and end-stage renal disease in African Americans.
Hypertension, diabetes mellitus and chronic glomerular diseases reportedly cause in excess of 80% of the incident cases of end… 
Highly Cited
1992
Highly Cited
1992
Cyclic AMP induces transforming growth factor beta 2 gene expression and growth arrest in the human androgen-independent prostate carcinoma cell line PC-3.
  • Y. Bang, S. Kim, J. Trepel
  • Proceedings of the National Academy of Sciences…
  • 1992
  • Corpus ID: 43381396
The standard therapy for advanced prostate cancer is androgen ablation. Despite transitory responses, hormonally treated patients… 
Highly Cited
1990
Highly Cited
1990
Co-localization of transforming growth factor beta 2 with alpha 1(I) procollagen mRNA in tissue sections of patients with systemic sclerosis.
The role of transforming growth factor beta 2 (TGF-beta 2) in the pathogenesis of systemic sclerosis (SSc) was investigated by in… 
Highly Cited
1989
Highly Cited
1989
Monoclonal antibodies recognizing transforming growth factor-beta. Bioactivity neutralization and transforming growth factor beta 2 affinity purification.
Four mAb able to recognize transforming growth factor-beta 2 (TGF-beta)2 were obtained. One of these mAb, 1D11.16, was able to… 
Highly Cited
1989
Highly Cited
1989
Inhibition of lymphocyte function by glioblastoma-derived transforming growth factor beta 2.
Human glioblastoma cells secrete an inhibitory factor termed "glioblastoma-derived T-cell suppressor factor" (G-TsF). A member of… 
Highly Cited
1989
Highly Cited
1989
Expression of transforming growth factor beta 2 RNA during murine embryogenesis.
We have studied the temporal and spatial expression of transforming growth factor beta 2 (TGF beta 2) RNA in mouse embryos from… 
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