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Current understanding of molecular and cellular mechanisms in fibroplasia and angiogenesis during acute wound healing.
This review integrates in vitro, animal and human in vivo studies, to provide up to date descriptions of molecular and cellular interactions involved in fibroplasia and angiogenesis. Expand
Scientific understanding and clinical management of Dupuytren disease
A detailed update of the scientific understanding of Dupuytren disease and its clinical management is provided, with perspectives on emerging research and therapy. Expand
Genetics of keloid scarring
  • B. Shih, A. Bayat
  • Biology, Medicine
  • Archives of Dermatological Research
  • 4 February 2010
A varied inheritance pattern in KD is indicated (predominantly autosomal dominant), linkage loci (chromosomes 2q23 and 7p11), several human leukocyte antigen alleles (HLA-DRB1*15, HLA-DQA1*0104), negative candidate gene case–control association studies and at least 25 dysregulated genes reported in multiple microarray studies. Expand
Skin scarring
Deciding whether to treat a scar or leave it alone depends on accurate diagnosis of scar type and scar site, symptoms, severity, and stigma
Molecular dissection of abnormal wound healing processes resulting in keloid disease
A detailed account of individual phases of the healing process and how they may potentially be implicated in aberrant raised scar formation is presented, which may help in clarifying the mechanisms involved in keloid disease pathogenesis. Expand
Epidemiological Evaluation of Dupuytren’s Disease Incidence and Prevalence Rates in Relation to Etiology
The prevalence of DD in different geographical locations is extremely variable, and it is not clear whether this is genetic, environmental, or a combination of both. Expand
Dupuytren's diathesis revisited: Evaluation of prognostic indicators for risk of disease recurrence.
The presence of all new DD diathesis factors in a patient increases the risk of recurrent DD by 71% compared with a baseline risk of 23% in those DD patients with none of the earlier-described factors. Expand
Electrical Stimulation in Bone Healing: Critical Analysis by Evaluating Levels of Evidence
Overall, the studies, although in favor of ES application in bone repair, displayed variability in treatment regime, primary outcome measures, follow-up times, and study design, making critical evaluation and assessment difficult. Expand
Striae distensae: a comprehensive review and evidence‐based evaluation of prophylaxis and treatment
Treatments that are evaluated include topical agents, used prophylactically or therapeutically, as well as light and laser therapies, which have shown improvements in the appearance of striae. Expand
Keloid disease: clinical relevance of single versus multiple site scars.
It is concluded that in this particular study group female sex, younger age at presentation and the presence of a positive family history were associated with the development of keloid scars in multiple anatomical sites in Afrocaribbean individuals. Expand