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TFRC protein, human

Known as: TfR, Transferrin Receptor 1, TFRC 
Transferrin receptor protein 1 (760 aa, ~85 kDa) is encoded by the human TFRC gene. This protein plays a role in the transport of iron into cells.
National Institutes of Health

Related topics

Related topics

20 relations

Broader (1)

CD71 antigen
Cellular MembraneErythropoiesisIntegral Membrane ProteinsIonophore activity

Papers overview

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Highly Cited
2005
Highly Cited
2005
Delivery of β-Galactosidase to Mouse Brain via the Blood-Brain Barrier Transferrin Receptor
Enzyme replacement therapy of lysosomal storage disorders is complicated by the lack of enzyme transport across the blood-brain… 
Highly Cited
2002
Highly Cited
2002
Imaging gene expression in the brain in vivo in a transgenic mouse model of Huntington's disease with an antisense radiopharmaceutical and drug-targeting technology.
UNLABELLED Disease-specific genes of unknown function can be imaged in vivo with antisense radiopharmaceuticals, providing the… 
Highly Cited
1998
Highly Cited
1998
Meat intake and iron status in late infancy: an intervention study.
BACKGROUND Highly bioavailable dietary iron is needed to ensure optimal iron status in infants during weaning. The purpose of the… 
Review
1998
Review
1998
Regulation of Transferrin Function and Expression: Review and Update
The cellular iron uptake is a precisely controlled process to fulfill the iron demand for the synthesis and functions of a… 
Highly Cited
1993
Highly Cited
1993
Subsets of CD8 +, CD57+ cells in normal, healthy individuals: correlations with human cytomegalovirus (HCMV) carrier status, phenotypic and functional analyses
Two different subsets of CD8 +, CD57+ cells have been defined, one expressing high levels (CD8high+(CD57+)), the other expressing… 
Highly Cited
1991
Highly Cited
1991
Translation and the stability of mRNAs encoding the transferrin receptor and c-fos.
Turnover of the full-length human transferrin receptor (TfR) mRNA is regulated by iron, and this regulation is mediated by the… 
Highly Cited
1985
Highly Cited
1985
Intracellular movement of cell surface receptors after endocytosis: resialylation of asialo-transferrin receptor in human erythroleukemia cells
The intracellular movement of cell surface transferrin receptor (TfR) after internalization was studied in K562 cultured human… 
Highly Cited
1982
Highly Cited
1982
Synthetic peptide substrates for a tyrosine protein kinase.
Highly Cited
1980
Highly Cited
1980
Abelson murine leukemia virus mutants deficient in kinase activity and lymphoid cell transformation
Abelson murine leukemia virus transforms both lymphoid cells and fibroblasts in vitro and induces a unique type of thymus… 
Highly Cited
1975
Highly Cited
1975
Effect of alcohol and task on hemispheric asymmetry of visually evoked potentials in man.
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