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TFF2 gene

Known as: Trefoil Factor 2 Gene, TFF2, SP 
This gene is involved in the inhibition of both gastric acid secretion and gastrointestinal motility.
National Institutes of Health

Related topics

Related topics

4 relations
DigestionGastric Acid Secretion InhibitionTFF2 protein, humanTrefoil Factor-2

Papers overview

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Highly Cited
2010
Highly Cited
2010
Cytodifferentiation of the postnatal mouse stomach in normal and Huntingtin-interacting protein 1-related-deficient mice.
Huntingtin-interacting protein 1-related (Hip1r) is highly expressed in gastric parietal cells, where it participates in… 
Highly Cited
2007
Highly Cited
2007
Accelerated progression of gastritis to dysplasia in the pyloric antrum of TFF2 -/- C57BL6 x Sv129 Helicobacter pylori-infected mice.
Trefoil factor family 2 (TFF2) is up-regulated in Helicobacter spp.-infected gastric tissues of both humans and mice. To… 
2006
2006
Systemically administered trefoil factors are secreted into the gastric lumen and increase the viscosity of gastric contents
Trefoil factors (TFFs) secreted by mucus‐producing cells are essential for the defence of the gastrointestinal mucosa. TFFs… 
Highly Cited
2004
Highly Cited
2004
Immunoassays of human trefoil factors 1 and 2: measured on serum from patients with inflammatory bowel disease
Background: The trefoil factors (TFF1–3) are cysteine‐rich peptides expressed in the gastrointestinal tract where they play a… 
Highly Cited
2004
Highly Cited
2004
Epidermal growth factor and trefoil factor family 2 synergistically trigger chemotaxis on BEAS-2B cells via different signaling cascades.
Injured areas of the respiratory epithelium are subject to rapid repair by the migration of adjacent epithelial cells, a process… 
2003
2003
Expression of TFF2 and Helicobacter pylori infection in carcinogenesis of gastric mucosa.
AIM To investigate the expression of TFF2 and Helicobacter pylori infection in carcinogenesis of gastric mucosa. METHODS The… 
Highly Cited
2001
Highly Cited
2001
Nuclear transfer in cattle with non‐transfected and transfected fetal or cloned transgenic fetal and postnatal fibroblasts
The efficiency of nuclear transfer (NT) using two primary cultures of fetal fibroblasts (FF1 and FF2) was compared vs. the same… 
Highly Cited
2000
Highly Cited
2000
Isolation and characterization of putative trefoil peptide receptors
Highly Cited
1999
Highly Cited
1999
Trefoil factor-2, human spasmolytic polypeptide, promotes branching morphogenesis in MCF-7 cells.
Members of the trefoil factor (TFF) family are highly expressed in endodermal ulcerative wound healing and selectively in… 
1999
1999
Patterns of expression of trefoil peptides and mucins in gastric polyps with and without malignant transformation
The expression of two trefoil peptides (TFF1 and TFF2) and four mucins (MUC1, MUC2, MUC5AC, and MUC6) was evaluated by… 
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