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TFF2 gene

Known as: Trefoil Factor 2 Gene, TFF2, SP 
This gene is involved in the inhibition of both gastric acid secretion and gastrointestinal motility.
National Institutes of Health

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4 relations
DigestionGastric Acid Secretion InhibitionTFF2 protein, humanTrefoil Factor-2

Papers overview

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2019
2019
The TFF Peptides xP1 and xP4 Appear in Distinctive Forms in the Xenopus laevis Gastric Mucosa: Indications for Different Protective Functions
The gastric secretory trefoil factor family (TFF) peptides xP1 and xP4 are the Xenopus laevis orthologs of mammalian TFF1 and… 
2014
2014
Chronic rhinosinusitis without nasal polyps is associated with increased expression of trefoil factor family peptides
Trefoil factor family (TFF) peptides are mucin‐associated secretory products that are produced in the airways and… 
2012
2012
Trefoil Factor Family Peptides in Normal and Diseased Human Pancreas
Objectives Trefoil factor family (TFF) peptides promote wound healing in the gut. Recent evidence has suggested that TFF3 may be… 
2006
2006
Altered metaplastic response of waved-2 EGF receptor mutant mice to acute oxyntic atrophy.
Metaplastic cell lineages are putative precursors for the development of gastric adenocarcinoma. The loss of parietal cells… 
2005
2005
Reciprocal changes in trefoil 1 and 2 expression in stomachs of mice with gastric unit hypertrophy and inflammation
H+/K+‐ATPase β‐subunit‐deficient mice (129/Sv background) display numerous pathologies in the stomach. Expression of the mutation… 
Highly Cited
2004
Highly Cited
2004
Immunoassays of human trefoil factors 1 and 2: measured on serum from patients with inflammatory bowel disease
Background: The trefoil factors (TFF1–3) are cysteine‐rich peptides expressed in the gastrointestinal tract where they play a… 
2004
2004
Expression and motogenic activity of TFF2 in human breast cancer cells
2003
2003
Preventive effect of hydrotalcite on gastric mucosal injury in rats induced by taurocholate.
AIM To study the preventive effect of hydrotalcite on gastric mucosal injury in rat induced by taurocholate, and to investigate… 
1999
1999
Patterns of expression of trefoil peptides and mucins in gastric polyps with and without malignant transformation
The expression of two trefoil peptides (TFF1 and TFF2) and four mucins (MUC1, MUC2, MUC5AC, and MUC6) was evaluated by… 
1998
1998
A novel 25 bp tandem repeat within the human trefoil peptide gene TFF2 in 21q22.3: polymorphism and mammalian evolution
Trefoil peptides belong to a family of small secretory proteins characterised by three intrachain disulfide bonds forming the… 
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