TERF2IP gene

Known as: TERF2IP, TERF2 interacting protein, RAP1 
This gene is involved in both telomere maintenance and gene transcription.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1989-2017
051019892017

Related topics

Related topics

4 relations
TERF2 geneTelomere MaintenanceTelomeric Repeat-Binding Factor 2-Interacting Protein 1Transcriptional Regulation

Related mentions per year

Related mentions per year

1967-2018
1960198020002020
TERF2IP gene
Transcriptional Regulation
Telomere Maintenance
Telomeric Repeat-Binding Factor 2-Interacting Protein 1
TERF2 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Human telomeric proteins occupy selective interstitial sites
Human telomeres are bound and protected by protein complexes assembled around the six core telomeric proteins RAP1, TRF1, TRF2… (More)
  • figure 1
  • table 1
  • table 2
  • figure 2
  • table 3
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Rap1-mediated activation of extracellular signal-regulated kinases by cyclic AMP is dependent on the mode of Rap1 activation.
Like other small G proteins of the Ras superfamily, Rap1 is activated by distinct guanine nucleotide exchange factors (GEFs) in… (More)
Is this relevant?
Highly Cited
2004
Highly Cited
2004
The transcription factor Ifh1 is a key regulator of yeast ribosomal protein genes
Ribosomal protein (RP) genes in eukaryotes are coordinately regulated in response to growth stimuli and environmental stress… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Relationships between Rap1b, affinity modulation of integrin alpha IIbbeta 3, and the actin cytoskeleton.
The affinity of integrin alpha(IIb)beta(3) for fibrinogen is controlled by inside-out signals that are triggered by agonists like… (More)
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Telomere binding of the Rap1 protein is required for meiosis in fission yeast
Telomeres are essential for chromosome integrity, protecting the ends of eukaryotic linear chromosomes during cell proliferation… (More)
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
1995
Highly Cited
1995
Action of a RAP1 carboxy-terminal silencing domain reveals an underlying competition between HMR and telomeres in yeast.
RAP1 is a sequence-specific DNA-binding protein in yeast that can either repress or activate transcription. Previous studies have… (More)
Is this relevant?
1995
1995
The carboxy termini of Sir4 and Rap1 affect Sir3 localization: evidence for a multicomponent complex required for yeast telomeric silencing
The Silent Information Regulatory proteins, Sir3 and Sir4, and the telomeric repeat-binding protein RAP1 are required for the… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1994
Highly Cited
1994
Evidence that a complex of SIR proteins interacts with the silencer and telomere-binding protein RAP1.
The maintenance of transcriptional silencing at HM mating-type loci and telomeres in yeast requires the SIR2, SIR3, and SIR4… (More)
Is this relevant?
Highly Cited
1994
Highly Cited
1994
Protein kinase A mediates growth-regulated expression of yeast ribosomal protein genes by modulating RAP1 transcriptional activity.
Yeast ribosomal protein genes are coordinately regulated as a function of cell growth; RNA levels decrease during amino acid… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
1991
1991
RAP1 protein activates and silences transcription of mating-type genes in yeast.
RAP1 is a sequence-specific DNA-binding protein essential for cell growth. The occurrence of RAP1-binding sites in many promoter… (More)
Is this relevant?