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TERF2IP gene

Known as: TERF2IP, TERF2 interacting protein, RAP1 
This gene is involved in both telomere maintenance and gene transcription.
National Institutes of Health

Related topics

Related topics

4 relations
TERF2 geneTelomere MaintenanceTelomeric Repeat-Binding Factor 2-Interacting Protein 1Transcriptional Regulation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
The orientation of the C-terminal domain of the Saccharomyces cerevisiae Rap1 protein is determined by its binding to DNA
Rap1 is an essential DNA-binding factor from the yeast Saccharomyces cerevisiae involved in transcription and telomere… 
Review
2005
Review
2005
Genetic variation, nucleotide diversity, and linkage disequilibrium in seven telomere stability genes suggest that these genes may be under constraint
To maintain chromosomal integrity and to protect the ends of chromosomes against recognition as damaged DNA, end‐to‐end fusion… 
2001
2001
The N-terminal and C-terminal Domains of RAP1 Are Dispensable for Chromatin Opening and GCN4-mediated HIS4 Activation in Budding Yeast*
Repressor activator protein 1 (RAP1) assists GCN4-mediated HIS4 activation by overcoming some repressive aspect of chromatin… 
2000
2000
Activation of the Ras‐related GTPase Rap1 by thymocyte TCR engagement and during selection
Signals mediated by activation of the small GTPase Ras play an essential role both in thymocyte development and in TCR‐mediated… 
Highly Cited
1996
Highly Cited
1996
Genetic analysis of Rap1p/Sir3p interactions in telomeric and HML silencing in Saccharomyces cerevisiae.
We have identified three SIR3 suppressors of the telomeric silencing defects conferred by missense mutations within the Rap1p C… 
Highly Cited
1994
Highly Cited
1994
Mutational analysis defines a C-terminal tail domain of RAP1 essential for Telomeric silencing in Saccharomyces cerevisiae.
Alleles specifically defective in telomeric silencing were generated by in vitro mutagenesis of the yeast RAP1 gene. The most… 
Highly Cited
1994
Highly Cited
1994
Isolation and functional analysis of a Kluyveromyces lactis RAP1 homologue.
Highly Cited
1992
Highly Cited
1992
Dissection of a carboxy-terminal region of the yeast regulatory protein RAP1 with effects on both transcriptional activation and silencing
RAP1 is an essential sequence-specific DNA-binding protein in Saccharomyces cerevisiae whose binding sites are found in a large… 
Highly Cited
1991
Highly Cited
1991
RAP1 protein activates and silences transcription of mating-type genes in yeast.
1990
1990
Phosphorylation influences the binding of the yeast RAP1 protein to the upstream activating sequence of the PGK gene.
Yeast repressor activator protein 1 (RAP1) binds in vitro to specific DNA sequences that are found in diverse genetic elements… 
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