TERF1 wt Allele

Known as: Telomeric Repeat Binding Factor (NIMA-Interacting) 1 wt Allele, TRF1, TERF1 
Human TERF1 wild-type allele is located in the vicinity of 8q13 and is approximately 39 kb in length. This allele, which encodes telomeric repeat… (More)
National Institutes of Health

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Highly Cited
2004
Highly Cited
2004
Human telomeres contain two related telomeric DNA-binding proteins, TRF1 and TRF2. The TRF1 complex contains the TRF1 interacting… (More)
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Highly Cited
2004
Highly Cited
2004
Human telomere length is controlled by a negative feedback loop based on the binding of TRF1 to double-stranded telomeric DNA… (More)
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Highly Cited
2004
Highly Cited
2004
In mammalian cells, telomere-binding proteins TRF1 and TRF2 play crucial roles in telomere biology. They interact with several… (More)
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Highly Cited
2004
Highly Cited
2004
Telomere length in humans is partly controlled by a feedback mechanism in which telomere elongation by telomerase is limited by… (More)
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Highly Cited
2003
Highly Cited
2003
Human telomere maintenance is essential for the protection of chromosome ends, and changes in telomere length have been… (More)
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Highly Cited
2000
Highly Cited
2000
Human telomeres are maintained by telomerase, a reverse transcriptase that adds telomeric repeats to chromosome ends [1,2]. In… (More)
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Highly Cited
2000
Highly Cited
2000
Telomeres are specialized DNA/protein structures that act as protective caps to prevent end fusion events and to distinguish the… (More)
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Highly Cited
1998
Highly Cited
1998
Tankyrase, a protein with homology to ankyrins and to the catalytic domain of poly(adenosine diphosphate-ribose) polymerase (PARP… (More)
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Highly Cited
1997
Highly Cited
1997
Human telomeres are composed of long arrays of TTAGGG repeats that form a nucleoprotein complex required for the protection and… (More)
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Highly Cited
1997
Highly Cited
1997
TRF1 is a mammalian telomeric protein that binds to the duplex array of TTAGGG repeats at chromosome ends. TRF1 has homology to… (More)
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