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TERF1 gene

Known as: TRF1, TELOMERIC REPEAT-BINDING FACTOR 1, Telomeric Repeat Binding Factor (NIMA-Interacting) 1 Gene 
This gene plays a role in telomere length maintenance and the inhibition of telomerase activity.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Not Broken Until Repaired Humans, and indeed most eukaryotes, have linear chromosomes with two DNA ends, known as telomeres… Expand
Highly Cited
2009
Highly Cited
2009
Telomeres protect chromosome ends through the interaction of telomeric repeats with shelterin, a protein complex that represses… Expand
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Highly Cited
2006
Highly Cited
2006
Root gravitropism describes the orientation of root growth along the gravity vector and is mediated by differential cell… Expand
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Review
2005
Review
2005
Added by telomerase, arrays of TTAGGG repeats specify the ends of human chromosomes. A complex formed by six telomere-specific… Expand
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Highly Cited
2004
Highly Cited
2004
Telomere maintenance has been implicated in cancer and ageing, and requires cooperation between a multitude of telomeric factors… Expand
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Highly Cited
2003
Highly Cited
2003
Human telomere maintenance is essential for the protection of chromosome ends, and changes in telomere length have been… Expand
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Highly Cited
2000
Highly Cited
2000
ABSTRACT Telomere length in human cells is controlled by a homeostasis mechanism that involves telomerase and the negative… Expand
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Highly Cited
1999
Highly Cited
1999
Mammalian telomeres contain a duplex array of telomeric repeats bound to the telomeric repeat-binding factors TRF1 and TRF2… Expand
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Highly Cited
1997
Highly Cited
1997
Human telomeres, the nucleoprotein complexes at chromosome ends, consist of tandem arrays of TTAGGG repeats bound to specific… Expand
Highly Cited
1997
Highly Cited
1997
Human telomeres are composed of long arrays of TTAGGG repeats that form a nucleoprotein complex required for the protection and… Expand