Telomere Length Maintenance

Known as: Length Maintenance, Length Maintenance, Telomere, Maintenance, Telomere Length 
Telomeres in human cancer cells consist of a tandem array of telomeric DNA repeats bound to a specialized telomeric proteins. Telomeres allow cells… (More)
National Institutes of Health

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Topic mentions per year

1976-2018
0102019762018

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2008
2008
CONTEXT Adrenocortical cancer (ACC) is a rare disease with an often fatal outcome. The clinical and pathological diagnosis of a… (More)
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Highly Cited
2006
Highly Cited
2006
Dyskeratosis congenita (DC) patients suffer a progressive and ultimately fatal loss of hematopoietic renewal correlating with… (More)
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2005
Highly Cited
2005
Cellular telomere length is linked to replicative life span. Telomere repeats are lost in peripheral blood cells in vivo by age… (More)
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2003
2003
The homologous recombination (HR) DNA repair pathway participates in telomere length maintenance in yeast but its putative role… (More)
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Highly Cited
2003
Highly Cited
2003
The human telomeric DNA binding factor TRF1 (hTRF1) and its interacting proteins TIN2, tankyrase 1 and 2, and PINX1 have been… (More)
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2002
2002
DNA-PKcs is the catalytic subunit of the DNA-dependent protein kinase (DNA-PK) complex that functions in the non-homologous end… (More)
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2000
Highly Cited
2000
Nijmegen breakage syndrome, a chromosomal instability disorder, is characterized in part by cellular hypersensitivity to ionizing… (More)
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1998
Highly Cited
1998
Tankyrase, a protein with homology to ankyrins and to the catalytic domain of poly(adenosine diphosphate-ribose) polymerase (PARP… (More)
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Highly Cited
1998
Highly Cited
1998
In the budding yeast, Saccharomyces cerevisiae, genes in close proximity to telomeres are subject to transcriptional silencing… (More)
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Highly Cited
1997
Highly Cited
1997
To examine the role of telomerase in normal and neoplastic growth, the telomerase RNA component (mTR) was deleted from the mouse… (More)
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