TEK wt Allele

Known as: TIE2, TEK, TEK Tyrosine Kinase, Endothelial (Venous Malformations, Multiple Cutaneous and Mucosal) wt Allele 
Human TEK wild-type allele is located within 9p21 and is approximately 121 kb in length. This allele, which encodes angiopoietin-1 receptor protein… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Tumor-derived exosomes are emerging mediators of tumorigenesis. We explored the function of melanoma-derived exosomes in the… (More)
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Highly Cited
2009
Highly Cited
2009
Angiopoietin 2 (Ang2) was originally shown to be a competitive antagonist for Ang1 of the receptor tyrosine kinase Tie2 in… (More)
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Highly Cited
2008
Highly Cited
2008
Tie2 belongs to the receptor tyrosine kinase family and functions as a receptor for Angiopoietin-1 (Ang1). Gene-targeting… (More)
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Highly Cited
2008
Highly Cited
2008
The receptor tyrosine kinase Tie2, and its activating ligand Angiopoietin-1 (Ang1), are required for vascular remodelling and… (More)
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Highly Cited
2004
Highly Cited
2004
The quiescent state is thought to be an indispensable property for the maintenance of hematopoietic stem cells (HSCs… (More)
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Highly Cited
1998
Highly Cited
1998
Angiopoietin-1 (Ang1) has been recently identified as the major physiological ligand for the tyrosine kinase receptor Tie2 and… (More)
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Highly Cited
1998
Highly Cited
1998
Sprouting of new capillaries from pre-existing blood vessels is a hallmark of angiogenesis during embryonic development and solid… (More)
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Highly Cited
1998
Highly Cited
1998
Angiopoietin-1 and its putative natural antagonist, angiopoietin-2, were recently isolated, and the critical role of angiopoietin… (More)
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Highly Cited
1997
Highly Cited
1997
Angiogenesis, the process of new vessels sprouting from the existing vasculature, is a critical process during early development… (More)
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Highly Cited
1996
Highly Cited
1996
TIE2 is a receptor-like tyrosine kinase expressed almost exclusively in endothelial cells and early hemopoietic cells and… (More)
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