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9p21

A chromosome band present on 9p
National Institutes of Health

Related topics

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6 relations
CDKN2A wt AlleleCDKN2B wt AlleleChromosome 9 Short ArmChromosomes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Loss of function of p16 gene and prognosis of pulmonary adenocarcinoma
Stepwise progression of peripheral‐type lung adenocarcinoma was characterized morphologically and was related to prognosis… 
Highly Cited
2001
Highly Cited
2001
Accumulative increase of loss of heterozygosity from leukoplakia to foci of early cancerization in leukoplakia of the oral cavity
Oral leukoplakia is a premalignant lesion, but the genetic changes in the foci of early cancerization in leukoplakia have not… 
Highly Cited
2000
Highly Cited
2000
p16 is a major inactivation target in hepatocellular carcinoma
The p16INK4A gene encodes 2 cell cycle regulator proteins, p16 and p14ARF, by alternative splicing. This genetic locus also… 
Highly Cited
1999
Highly Cited
1999
Loss of heterozygosity at chromosome 9p21 (INK4-p14ARF locus): homozygous deletions and mutations in the p16 and p14ARF genes in sporadic primary melanomas.
Loss of heterozygosity (LOH) was determined in 45 sporadic primary melanomas at six polymorphic microsatellite markers that flank… 
Highly Cited
1998
Highly Cited
1998
p16INK4a expression is frequently decreased and associated with 9p21 loss of heterozygosity in sporadic melanoma
The product of the p16/INK4a/CDKN2/MTS1 tumor‐suppressor gene acts as a negative cell cycle regulator by inhibiting G1 cyclin… 
Review
1997
Review
1997
Advances in the analysis of chromosome alterations in human lung carcinomas.
Highly Cited
1996
Highly Cited
1996
Alterations of the p15, p16,and p18 genes in osteosarcoma.
Highly Cited
1996
Highly Cited
1996
The gene for multiple familial trichoepithelioma maps to chromosome 9p21.
Multiple familial trichoepithelioma (MFT) is an autosomal dominant skin disease characterized by the presence of many small… 
Highly Cited
1994
Highly Cited
1994
Homozygous deletion on chromosome 9p and loss of heterozygosity on 9q, 6p, and 6q in primary human small cell lung cancer.
Review
1987
Review
1987
Abnormalities of the short arm of chromosome 9 with partial loss of material in hematological disorders.
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