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TDP1 wt Allele

Known as: FLJ11090, SCAN1, Tyrosyl-DNA Phosphodiesterase 1 wt Allele 
Human TDP1 wild-type allele is located in the vicinity of 14q32.11 and is approximately 90 kb in length. This allele, which encodes tyrosyl-DNA… 
National Institutes of Health

Related topics

Related topics

7 relations
DNA RepairDouble Strand Break RepairHydrolysisSPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE, WITH AXONAL NEUROPATHY

Broader (1)

TDP1 gene

Papers overview

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2014
2014
Repair of apurinic/apyrimidinic sites in single-stranded DNA initiated by tyrosyl-DNA phosphodiesterase 1
68 TyrosyllDNA phosphodiesterase 1 (Tdp1) is an enzyme that prevents the accumulation of covalent adducts of topoisomerase I… 
2012
2012
Spinocerebellar Ataxia with Axonal Neuropathy (SCAN1): A Disorder of Nuclear and Mitochondrial DNA Repair
Spinocerebellar ataxias (SCAs) are a group of progressive and irreversible neurological diseases affecting gait and movement… 
2010
2010
Abstract 3645: Functional analysis of tyrosyl-DNA phosphodiesterase 1 catalytic residues
Tyrosyl-DNA phosphodiesterase 1 (Tdp1) is a highly conserved eukaryotic DNA repair enzyme that hydrolyses 3′phospho-DNA adducts… 
2006
2006
Spinocerebellar ataxia with axonal neuropathy (SCAN1) (特集 脊髄小脳変性症研究の最近の進歩) -- (常染色体劣性遺伝性脊髄小脳変性症)
Review
2006
Review
2006
[Molecular genetics of inherited neuropathies].
To clarify the specific features and molecular mechanisms of five diseases that we previously reported, we reviewed recent… 
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