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TCF4 wt Allele

Known as: ITF-2, SEF2-1B, SEF2-1 
Human TCF4 wild-type allele is located 18q21.1 and is approximately 442 kb in length. This allele, which encodes transcription factor 4 protein, is… 
National Institutes of Health

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Related topics

3 relations
Homo sapiensTranscriptional Regulationdna binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Partial deletion of TCF4 in three generation family with non-syndromic intellectual disability, without features of Pitt-Hopkins syndrome.
2013
2013
Parent–child exome sequencing identifiesa de novo truncating mutation in TCF4 in non‐syndromic intellectual disability
To the Editor : Autosomal dominant mutations in the transcription factor TCF4 cause Pitt–Hopkins syndrome (PTHS; MIM#610954… 
2012
2012
Inhibition of Tcf-4 Induces Apoptosis and Enhances Chemosensitivity of Colon Cancer Cells
Aberrant activation of β-catenin/Tcf-4 signaling has been implicated in human carcinogenesis, including colorectal cancer. In… 
2008
2008
Gamma-Secretase-Dependent and -Independent Effects of Presenilin1 on β-Catenin·Tcf-4 Transcriptional Activity
Presenilin1 (PS1) is a component of the γ-secretase complex mutated in cases of Familial Alzheimer's disease (FAD). PS1 is… 
2006
2006
Positive Inter-Regulation between β-Catenin/T Cell Factor-4 Signaling and Endothelin-1 Signaling Potentiates Proliferation and Survival of Prostate Cancer Cells
Both malignant and normal prostate epithelial cells produce endothelin-1 (ET-1), a critical factor in prostate cancer (CaP… 
2006
2006
A PTH Reliability Model Considering Barrel Stress Distributions and Multiple PTHs in a PWB
Plated through hole (PTH) failure due to CTE-mismatch-induced fatigue is a major interconnection failure in electronic products… 
2006
2006
Role of the basic helix‐loop‐helix protein ITF2 in the hormonal regulation of Sertoli cell differentiation
Sertoli cells are a post‐mitotic terminally differentiated cell population that forms the seminiferous tubules in the adult… 
Review
2005
Review
2005
Parathyroid hormone (PTH) and hematopoiesis: New support for some old observations
Forty‐seven years ago, the parathyroid hormone (PTH) in one injection of Lilly's old bovine parathyroid extract, PTE, was found… 
2005
2005
Ionomycin downregulates beta-catenin/Tcf signaling in colon cancer cell line.
Functional activation of beta-catenin/Tcf signaling plays an important role in the early events in colorectal carcinogenesis. We… 
Highly Cited
1999
Highly Cited
1999
A Possible Role for the High Mobility Group Box Transcription Factor Tcf-4 in Vertebrate Gut Epithelial Cell Differentiation*
The Wingless (Wg)/Wnt signaling pathway activates High Mobility Group (HMG)-box transcription factors of the T-cell Factor (Tcf… 
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