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ABSTRACT Complex functional coupling exists between transcriptional elongation and pre-mRNA alternative splicing. Pausing sites… Expand The coactivator-associated arginine methyltransferase CARM1 is recruited by many different transcription factors as a positive… Expand Human CA150, a transcriptional activator, binds to and is co-deposited with huntingtin during Huntington's disease. The second WW… Expand Transcriptional dysregulation caused by expanded polyglutamines (polyGlns) in huntingtin (htt) may be central to cell-autonomous… Expand ABSTRACT The human transcription factor CA150 modulates human immunodeficiency virus type 1 gene transcription and contains… Expand Using an interaction blot approach to search in the human nuclear proteome, we identified eight novel proteins that bind the… Expand Huntington's disease (HD) is a neurodegenerative disease caused by polyglutamine expansion in the protein huntingtin (htt… Expand ABSTRACT CA150 represses RNA polymerase II (RNAPII) transcription by inhibiting the elongation of transcripts. The FF repeat… Expand An approach for purifying nuclear proteins that bind directly to the hyperphosphorylated C-terminal repeat domain (CTD) of RNA… Expand ABSTRACT Tat protein strongly activates transcription from the human immunodeficiency virus type 1 (HIV-1) long terminal repeat… Expand