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The murine SCP3 gene is required for synaptonemal complex assembly, chromosome synapsis, and male fertility.
During meiosis, the homologous chromosomes pair and recombine. An evolutionarily conserved protein structure, the synaptonemal complex (SC), is located along the paired meiotic chromosomes. We haveExpand
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A nuclear cap-binding complex binds Balbiani ring pre-mRNA cotranscriptionally and accompanies the ribonucleoprotein particle during nuclear export
In vertebrates, a nuclear cap-binding complex (CBC) formed by two cap- binding proteins, CBP20 and CBP80, is involved in several steps of RNA metabolism, including pre-mRNA splicing and nuclearExpand
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  • Open Access
Localization of the N-terminus of SCP1 to the central element of the synaptonemal complex and evidence for direct interactions between the N-termini of SCP1 molecules organized head-to-head.
The synaptonemal complex (SC) is a meiosis-specific, tripartite structure essential for synapsis of homologous chromosomes; it contains a central element positioned between two lateral elements andExpand
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The Synaptonemal Complex Protein SCP3 Can Form Multistranded, Cross-striated Fibers In Vivo
The synaptonemal complex protein SCP3 is part of the lateral element of the synaptonemal complex, a meiosis-specific protein structure essential for synapsis of homologous chromosomes. We haveExpand
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  • Open Access
A Pre-mRNA-Binding Protein Accompanies the RNA from the Gene through the Nuclear Pores and into Polysomes
In the larval salivary glands of C. tentans, it is possible to visualize by electron microscopy how Balbiani ring (BR) pre-mRNA associates with proteins to form pre-mRNP particles, how theseExpand
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An actin–ribonucleoprotein interaction is involved in transcription by RNA polymerase II
To determine the function of actin in the cell nucleus, we sought to identify nuclear actin-binding proteins in the dipteran Chironomus tentans using DNase I-affinity chromatography. We identifiedExpand
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  • Open Access
Actin Bound to the Heterogeneous Nuclear Ribonucleoprotein Hrp36 Is Associated with Balbiani Ring mRNA from the Gene to Polysomes
In the salivary glands of the dipteran Chironomus tentans, a specific messenger ribonucleoprotein (mRNP) particle, the Balbiani ring (BR) granule, can be visualized during its assembly on the geneExpand
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The central region of the synaptonemal complex revealed in three dimensions.
The synaptonemal complex plays a key role in pairing of homologous chromosomes during meiosis. Its gross structure was already known by conventional electron microscopy, but only recently has it beenExpand
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Translocation of a specific premessenger ribonucleoprotein particle through the nuclear pore studied with electron microscope tomography
A specific premessenger ribonucleoprotein (RNP) particle in the salivary glands of the dipteran Chironomus tentans was studied with electron microscope tomography during translocation from the cellExpand
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A Look at Messenger RNP Moving through the Nuclear Pore
but nevertheless most of them are still unknown. The After the processing of pre–messenger RNA (pre-mRNA) nucleoproteins examined usually display characteristic, in the cell nucleus, the matureExpand
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