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TBP gene

Known as: TATA-box binding protein, TBP, TATA Sequence-Binding Protein Gene 
This gene plays an essential role in RNA polymerase II transcription and initiation.
National Institutes of Health

Related topics

Related topics

9 relations
Homo sapiensSPINOCEREBELLAR ATAXIA 17TATA-Box Binding ProteinTranscription Factor TFIID

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TBP wt Allele

Papers overview

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Highly Cited
1999
Highly Cited
1999
Binding of TBP to promoters in vivo is stimulated by activators and requires Pol II holoenzyme
In eukaryotes, transcriptional activators have been proposed to function by recruiting the RNA polymerase II (Pol II) machinery… 
Highly Cited
1997
Highly Cited
1997
Repression by Ume6 Involves Recruitment of a Complex Containing Sin3 Corepressor and Rpd3 Histone Deacetylase to Target Promoters
Highly Cited
1996
Highly Cited
1996
Drosophila TFIID binds to a conserved downstream basal promoter element that is present in many TATA-box-deficient promoters.
We describe the identification and characterization of a conserved downstream basal promoter element that is present in a subset… 
Highly Cited
1995
Highly Cited
1995
Human TAFII31 protein is a transcriptional coactivator of the p53 protein.
The p53 protein activates transcription of a target gene by binding to a specific DNA response element and interacting with the… 
Highly Cited
1994
Highly Cited
1994
Assembly of recombinant TFIID reveals differential coactivator requirements for distinct transcriptional activators
Highly Cited
1994
Highly Cited
1994
Human TAFII30 is present in a distinct TFIID complex and is required for transcriptional activation by the estrogen receptor
Highly Cited
1992
Highly Cited
1992
Dr1, a TATA-binding protein-associated phosphoprotein and inhibitor of class II gene transcription
Highly Cited
1992
Highly Cited
1992
The role of the TATA-binding protein in the assembly and function of the multisubunit yeast RNA polymerase III transcription factor, TFIIIB
Highly Cited
1990
Highly Cited
1990
Transcriptional activation by Sp1 as directed through TATA or initiator: specific requirement for mammalian transcription factor IID.
Transcription of mammalian genes by RNA polymerase II often begins at a specific nucleotide, whose location is determined either… 
Highly Cited
1985
Highly Cited
1985
Factors involved in specific transcription by human RNA polymerase II: analysis by a rapid and quantitative in vitro assay.
We describe a new assay system that allows a rapid, direct, and quantitative detection of promoter-dependent in vitro… 
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