TASP1 gene

Known as: Taspase, Threonine Aspartase, 1 Gene, dJ585I14.2, C20ORF13 
This gene plays a role in both proteolysis and transcriptional regulation.
National Institutes of Health

Related topics

Related topics

4 relations
HydrolysisProteolysisThreonine AspartaseTranscriptional Activation

Papers overview

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Review
2016
Review
2016
Cleaving for growth: threonine aspartase 1--a protease relevant for development and disease.
From the beginning of life, proteases are key to organismal development comprising morphogenesis, cellular differentiation, and… (More)
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2015
2015
Novel inhibitors for the protease Taspase1
SUCCINIMIDE PEPTIDES INHIBIT TASPASE COMPETITIVELY 124 6 Abstract The threonine protease Taspase1 is of high interest as new… (More)
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Highly Cited
2014
Highly Cited
2014
NOTCH1-RBPJ complexes drive target gene expression through dynamic interactions with superenhancers.
The main oncogenic driver in T-lymphoblastic leukemia is NOTCH1, which activates genes by forming chromatin-associated Notch… (More)
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2012
2012
Tapping into TASP1
 
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2012
2012
Tapping into TASP1
 
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2008
2008
EPS15R, TASP1, and PRPF3 are novel disease candidate genes targeted by HNF4alpha splice variants in hepatocellular carcinomas.
BACKGROUND & AIMS The orphan nuclear receptor HNF4alpha is a member of the hepatic transcription factor network. This protein… (More)
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2008
2008
Gene expression profile analysis of primary glioblastomas and non-neoplastic brain tissue: identification of potential target genes by oligonucleotide microarray and real-time quantitative PCR
The prognosis of glioblastomas is still extremely poor and the discovery of novel molecular therapeutic targets can be important… (More)
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2005
2005
Crystal structure of human Taspase1, a crucial protease regulating the function of MLL.
Taspase1 catalyzes the proteolytic processing of the mixed lineage leukemia (MLL) nuclear protein, which is required for… (More)
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2003
2003
Crystal structure of thermostable aspartase from Bacillus sp. YM55-1: structure-based exploration of functional sites in the aspartase family.
The crystal structure of the thermostable aspartase from Bacillus sp. YM55-1 has been solved and refined for 2.5A resolution data… (More)
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1999
1999
Purification and characterization of thermostable aspartase from Bacillus sp. YM55-1.
A thermostable aspartase was purified from a thermophile Bacillus sp. YM55-1 and characterized in terms of activity and stability… (More)
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