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TASP1 gene

Known as: Taspase, Threonine Aspartase, 1 Gene, dJ585I14.2, C20ORF13 
This gene plays a role in both proteolysis and transcriptional regulation.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
The highly conserved protease TASP1 not only takes part in critical site-specific proteolysis, but also plays an important role… Expand
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2019
2019
Chromosomal translocations of the Mixed-lineage leukemia 1 (MLL1) gene generate MLL chimeras that drive the pathogenesis of acute… Expand
Review
2016
Review
2016
From the beginning of life, proteases are key to organismal development comprising morphogenesis, cellular differentiation, and… Expand
2015
2015
Taspase 1 (TASP1) cleaves the mixed-lineage leukemia (MLL) and transcription factor (TF) IIA families of nuclear proteins to… Expand
Highly Cited
2013
Highly Cited
2013
Significance Studies focused on understanding how transcription factors control gene expression have shown that transcription… Expand
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Highly Cited
2008
Highly Cited
2008
The prognosis of glioblastomas is still extremely poor and the discovery of novel molecular therapeutic targets can be important… Expand
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2008
2008
BACKGROUND & AIMS The orphan nuclear receptor HNF4alpha is a member of the hepatic transcription factor network. This protein… Expand
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Highly Cited
2005
Highly Cited
2005
Taspase1 catalyzes the proteolytic processing of the mixed lineage leukemia (MLL) nuclear protein, which is required for… Expand
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2003
2003
The crystal structure of the thermostable aspartase from Bacillus sp. YM55-1 has been solved and refined for 2.5A resolution data… Expand
1999
1999
A thermostable aspartase was purified from a thermophile Bacillus sp. YM55-1 and characterized in terms of activity and stability… Expand