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Threonine Aspartase

Known as: EC 3.4.25.-, Threonine Aspartase 1, Taspase 1 
Threonine aspartase 1 (420 aa, ~44 kDa) is encoded by the human TASP1 gene. This protein plays a role in the proteolysis of histone-lysine N… Expand
National Institutes of Health

Papers overview

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2019
2019
We report four unrelated children with homozygous loss‐of‐function variants in TASP1 and an overlapping phenotype comprising… Expand
2018
2018
We report a 20p12.1 homozygous deletion including exons 5‐10 of the TASP1 gene in an infant with developmental delay, acquired… Expand
2018
2018
Transcription factor TFIIA is controlled by complex regulatory networks including proteolysis by the protease Taspase 1, though… Expand
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2015
2015
Taspase 1 (TASP1) cleaves the mixed-lineage leukemia (MLL) and transcription factor (TF) IIA families of nuclear proteins to… Expand
2014
2014
Taspase 1 is an N‐terminal threonine protease implicated in leukemia and other cancers. Despite intensive efforts in recent years… Expand
2010
2010
Authors' A Immunolog Missouri Note: Supp Online (http Correspon Washingto McDonnel 1508; Fax: 
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2008
2008
BACKGROUND & AIMS The orphan nuclear receptor HNF4alpha is a member of the hepatic transcription factor network. This protein… Expand
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Highly Cited
2007
Highly Cited
2007
ABSTRACT Site-specific proteolytic processing plays important roles in the regulation of cellular activities. The histone… Expand
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Highly Cited
2006
Highly Cited
2006
ABSTRACT In higher eukaryotes, the large subunit of the general transcription factor TFIIA is encoded by the single TFIIAαβ gene… Expand
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1990
1990
The hybridization of the native and chemically inactivated aspartase from Escherichia coli was studied. Preparations of the… Expand