Threonine Aspartase

Known as: EC 3.4.25.-, Threonine Aspartase 1, Taspase 1

Threonine aspartase 1 (420 aa, ~44 kDa) is encoded by the human TASP1 gene. This protein plays a role in the proteolysis of histone-lysine N… (More)

National Institutes of Health

2003-2016

Papers overview

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2017

Transcription factor TFIIA is controlled by complex regulatory networks including proteolysis by the protease Taspase 1, though… (More)

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2016

Proteases are involved in numerous pathobiological processes in oral cancer. Due to disappointing results with metalloproteinase… (More)

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2015

Taspase 1 (TASP1) cleaves the mixed-lineage leukemia (MLL) and transcription factor (TF) IIA families of nuclear proteins to… (More)

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2014

Taspase 1 is an N-terminal threonine protease implicated in leukemia and other cancers. Despite intensive efforts in recent years… (More)

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2011

BACKGROUND Threonine Aspartase 1 (Taspase1) mediates cleavage of the mixed lineage leukemia (MLL) protein and leukemia provoking… (More)

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Highly Cited

2003

Highly Cited

2003

The Mixed-Lineage Leukemia gene (MLL/HRX/ALL1) encodes a large nuclear protein homologous to Drosophila trithorax that is… (More)

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