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Threonine Aspartase

Known as: EC 3.4.25.-, Threonine Aspartase 1, Taspase 1 
Threonine aspartase 1 (420 aa, ~44 kDa) is encoded by the human TASP1 gene. This protein plays a role in the proteolysis of histone-lysine N… Expand
National Institutes of Health

Papers overview

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2019
2019
We report four unrelated children with homozygous loss-of-function variants in TASP1 and an overlapping phenotype comprising… Expand
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2018
2018
We report a 20p12.1 homozygous deletion including exons 5-10 of the TASP1 gene in an infant with developmental delay, acquired… Expand
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2018
2018
Transcription factor TFIIA is controlled by complex regulatory networks including proteolysis by the protease Taspase 1, though… Expand
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2016
2016
Proteases are involved in numerous pathobiological processes in oral cancer. Due to disappointing results with metalloproteinase… Expand
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2014
2014
Taspase 1 is an N-terminal threonine protease implicated in leukemia and other cancers. Despite intensive efforts in recent years… Expand
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2009
2009
Taspase1 is a threonine protease responsible for cleaving MLL (Mixed-Lineage Leukemia) to achieve proper HOX gene expression… Expand
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2008
2008
BACKGROUND & AIMS The orphan nuclear receptor HNF4alpha is a member of the hepatic transcription factor network. This protein… Expand
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2007
2007
Site-specific proteolytic processing plays important roles in the regulation of cellular activities. The histone modification… Expand
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2006
2006
In higher eukaryotes, the large subunit of the general transcription factor TFIIA is encoded by the single TFIIAalphabeta gene… Expand
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1990
1990
The hybridization of the native and chemically inactivated aspartase from Escherichia coli was studied. Preparations of the… Expand
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