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T-Type Calcium Channels

Known as: T-Type Voltage-Dependent Calcium Channels, T Type Voltage Dependent Calcium Channels, T-Type Calcium Channel 
A heterogenous group of transient or low voltage activated type CALCIUM CHANNELS. They are found in cardiac myocyte membranes, the sinoatrial node… 
National Institutes of Health

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CACNA1G protein, humanCacna1h protein, rat
In BloodProcess of secretionaspects of radiation effectschemical synthesis

Papers overview

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Highly Cited
2017
Highly Cited
2017
Targetable T-type Calcium Channels Drive Glioblastoma.
Glioblastoma (GBM) stem-like cells (GSC) promote tumor initiation, progression, and therapeutic resistance. Here, we show how… 
Review
2010
Review
2010
Contributions of T-type calcium channel isoforms to neuronal firing
Low voltage-activated (LVA) T-type calcium channels play critical roles in the excitability of many cell types and are a focus of… 
Highly Cited
2006
Highly Cited
2006
CaV3 T‐type calcium channel isoforms differentially distribute to somatic and dendritic compartments in rat central neurons
Spike output in many neuronal cell types is affected by low‐voltage‐activated T‐type calcium currents arising from the Cav3.1… 
Highly Cited
2006
Highly Cited
2006
Specific T-type calcium channel isoforms are associated with distinct burst phenotypes in deep cerebellar nuclear neurons.
T-type calcium channels are thought to transform neuronal output to a burst mode by generating low voltage-activated (LVA… 
Highly Cited
2002
Highly Cited
2002
Selective Coupling of T-Type Calcium Channels to SK Potassium Channels Prevents Intrinsic Bursting in Dopaminergic Midbrain Neurons
Dopaminergic midbrain (DA) neurons display two principal activity patterns in vivo, single-spike and burst firing, the latter… 
Highly Cited
2001
Highly Cited
2001
Direct inhibition of T‐type calcium channels by the endogenous cannabinoid anandamide
Low‐voltage‐activated or T‐type Ca2+ channels (T‐channels) are widely expressed, especially in the central nervous system where… 
Highly Cited
1999
Highly Cited
1999
Nickel block of three cloned T-type calcium channels: low concentrations selectively block alpha1H.
Highly Cited
1999
Highly Cited
1999
A T-type calcium channel from mouse brain
Abstract A member of the low-voltage-activated calcium channel family was identified in mouse brain by taking advantage of amino… 
Highly Cited
1990
Highly Cited
1990
Mechanism of gating of T-type calcium channels
We have analyzed the gating kinetics of T-type Ca channels in 3T3 fibroblasts. Our results show that channel closing… 
Review
1987
Review
1987
Calcium channels: mechanisms of selectivity, permeation, and block.
CONTENTS PERSPECTIVES AND OVERVIEW 265 SELECTIVITY BY REJECTION OR AFFINITY? 266 Permeability Sequence Derived from Reversal… 
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