Contributions of T-type calcium channel isoforms to neuronal firing.

  title={Contributions of T-type calcium channel isoforms to neuronal firing.},
  author={Stuart M. Cain and Terrance P. Snutch},
  volume={4 6},
Low voltage-activated (LVA) T-type calcium channels play critical roles in the excitability of many cell types and are a focus of research aimed both at understanding the physiological basis of calcium channel-dependent signaling and the underlying pathophysiology associated with hyperexcitability disorders such as epilepsy.  These channels play a critical role towards neuronal firing in both conducting calcium ions during action potentials and also in switching neurons between distinct modes… CONTINUE READING
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