Synaptotagmins

Known as: Synaptotagmin, Synaptotagmins [Chemical/Ingredient], Tagmin 
A family of vesicular transport proteins characterized by an N-terminal transmembrane region and two C-terminal calcium-binding domains.
National Institutes of Health

Papers overview

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Review
2008
Review
2008
Neurotransmitter release at synapses involves a highly specialized form of membrane fusion that is triggered by Ca(2+) ions and… (More)
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Highly Cited
2007
Highly Cited
2007
Synaptic vesicles loaded with neurotransmitters are exocytosed in a soluble N-ethylmaleimide-sensitive factor attachment protein… (More)
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Highly Cited
2006
Highly Cited
2006
Synaptic transmission is mediated by neurotransmitters that are stored in synaptic vesicles and released by exocytosis upon… (More)
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Highly Cited
2006
Highly Cited
2006
Ca(2+) binding to synaptotagmin 1 triggers fast exocytosis of synaptic vesicles that have been primed for release by SNARE… (More)
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Highly Cited
2003
Highly Cited
2003
Botulinum neurotoxins (BoNTs) cause botulism by entering neurons and cleaving proteins that mediate neurotransmitter release… (More)
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Highly Cited
2002
Highly Cited
2002
At nerve terminals, a focal and transient increase in intracellular Ca2+ triggers the fusion of neurotransmitter-filled vesicles… (More)
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Highly Cited
2001
Highly Cited
2001
In all synapses, Ca2+ triggers neurotransmitter release to initiate signal transmission. Ca2+ presumably acts by activating… (More)
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Highly Cited
1995
Highly Cited
1995
SYNAPTOTAGMINS (Syts) are brain-specific Ca2+/phospholipidbinding proteins1–5. In hippocampal synapses, Syt I is essential for… (More)
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Highly Cited
1994
Highly Cited
1994
Mice carrying a mutation in the synaptotagmin I gene were generated by homologous recombination. Mutant mice are phenotypically… (More)
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Highly Cited
1992
Highly Cited
1992
Neurons release neurotransmitters by calcium-dependent exocytosis of synaptic vesicles. However, the molecular steps transducing… (More)
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