Swainsonine

Known as: 1,2,8-Indolizinetriol, octahydro-, (1S-(1alpha,2alpha,8beta,8abeta))-, Swainsonine [Chemical/Ingredient] 
An indolizidine alkaloid from the plant Swainsona canescens that is a potent alpha-mannosidase inhibitor. Swainsonine also exhibits antimetastatic… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1980-2018
0204019802018

Papers overview

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Highly Cited
2010
Highly Cited
2010
Prions are infectious proteins consisting mainly of PrP(Sc), a beta sheet-rich conformer of the normal host protein PrP(C), and… (More)
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Highly Cited
2004
Highly Cited
2004
Cell surface CD147 shows remarkable variations in size (31-65 kDa) because of heterogeneous N-glycosylation, with the most highly… (More)
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2003
2003
Consumption of locoweeds, legumes endemic in arid western USA, has long been associated with locoism, a disease of ruminant… (More)
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Highly Cited
1999
Highly Cited
1999
Nonstructural glycoprotein NS1, specified by dengue virus type 1 (Den-1), is secreted from infected green monkey kidney (Vero… (More)
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1997
1997
The indolizidine alkaloid swainsonine, a potent inhibitor of Golgi alpha-mannosidase II, has been shown to reduce tumor cell… (More)
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1991
1991
The concentration of dopamine (DA) in the synaptic cleft in the mouse striatum in vivo was estimated from the competition between… (More)
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1985
1985
Swainsonine isolated from Metarhizium sp., was found to enhance the activities of the mouse immune system in vitro. Concanavalin… (More)
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1985
1985
The feeding deterrency of a series of pyrrolizidine, indolizidine, and quinolizidine alkaloids and selected derivatives was… (More)
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1981
1981
Swainsonine, an indolizidine alkaloid, inhibits the processing of asparagine-linked glycoproteins in both cell-free extracts and… (More)
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1980
1980
An indolizidine alkaloid (swainsonine) was isolated from the plant Swainsona canescens. Swainsonine is a specific and potent… (More)
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