Skip to search formSkip to main contentSkip to account menu

Sulindac

Known as: Sulindac [Chemical/Ingredient], 1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-, (Z)-, (Z)-5-fluoro-2-methyl-1-[[4-(methylsulfinyl)phenyl]methylene]-1H-indene-3-acetic acid 
A sulfinylindene derivative prodrug with potential antineoplastic activity. Converted in vivo to an active metabolite, sulindac, a nonsteroidal anti… 
National Institutes of Health

Related topics

Related topics

38 relations

Narrower (17)

AclinApo-SulinClinorilCopal

Broader (3)

Anti-Inflammatory Agents, Non-SteroidalAntineoplastic AgentsCyclooxygenase Inhibitors
Arthritis, GoutyDegenerative polyarthritisDrug AllergyIn Blood

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1986
1986
Effect of aspirin and sulindac in rabbit nephrotoxic nephritis.
Glomerular damage in nephrotoxic nephritis is mediated by circulating cells (neutrophils, platelets, and macrophages… 
1985
1985
Differential effects of sulindac and indomethacin on blood pressure in treated essential hypertensive subjects.
Attenuation of the effectiveness of antihypertensive therapy by non-steroidal anti-inflammatory (NSAI) drugs has been attributed… 
1984
1984
The influence of indomethacin and sulindac on some pharmacological actions of atenolol in hypertensive patients.
Indomethacin and sulindac were used as tools to study the role of renal and/or systemic prostaglandins in the pharmacological… 
1983
1983
Diabetic complications in lens and nerve and their prevention by sulindac or sorbinil: two novel aldose reductase inhibitors.
Sorbitol, resulting from glucose metabolism through aldose reductase, may play a role in diabetic complications such as cataracts… 
Highly Cited
1982
Highly Cited
1982
Sulindac-induced aseptic meningitis.
A 22-year-old woman with systemic lupus erythematosus experienced generalized pruritus, shortness of breath, pleuritic chest pain… 
1981
1981
Sulindac and pneumonitis.
Excerpt To the editor: An increasing number of drugs have been identified as causing hypersensitivity pneumonitis (1, 2… 
1981
1981
Sulfoxide reduction. In vitro reduction of sulindac by rat hepatic cytosolic enzymes.
The reductive biotransformation of sulindac to the corresponding sulfide has been characterized in vitro in rat preparations with… 
1980
1980
Life-threatening hypersensitivity to sulindac.
  • F. SmithP. Lindberg
  • Journal of the American Medical Association (JAMA…
  • 1980
  • Corpus ID: 26945164
LIFE-THREATENING hypersensitivity after administration of sulindac has not been reported, to our knowledge, although fatal… 
1967
1967
Some factors of significance in the double antibody immunoassay of insulin.
Differences were demonstrated between 4 insulin antibody (guinea pig) precipitating antisera (rabbit), int. al. in their ability… 
Highly Cited
1960
Highly Cited
1960
The kinetics of the reaction between antibody and bovine serum albumin using the Farr method.
Institute of Allergy and Infectious Diseases of the National Institutes of Health, U. S. Public Health Service. sulin are…