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Arthritis, Gouty

Known as: Gouty arthropathy, arthritis gout, gout arthritis 
Arthritis, especially of the great toe, as a result of gout. Acute gouty arthritis often is precipitated by trauma, infection, surgery, etc. The… Expand
National Institutes of Health

Papers overview

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Review
2013
Review
2013
IL-1 is a master cytokine of local and systemic inflammation. With the availability of specific IL-1 targeting therapies, a… Expand
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Highly Cited
2012
Highly Cited
2012
In response to a request for proposal from the American College of Rheumatology (ACR), our group was charged with developing non… Expand
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Highly Cited
2010
Highly Cited
2010
OBJECTIVE The concept that intraarticular crystals of uric acid by themselves trigger episodes of painful gouty arthritis is… Expand
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Highly Cited
2010
Highly Cited
2010
OBJECTIVE To assess the efficacy and tolerability of canakinumab, a fully human anti-interleukin-1β monoclonal antibody, for the… Expand
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Highly Cited
2009
Highly Cited
2009
Glyburide, a sulfonylurea drug commonly used to treat type 2 diabetes, shuts down IL-1β secretion by preventing Cyropyrin… Expand
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Highly Cited
2009
Highly Cited
2009
Background: Recent studies suggest that blockade of the NLRP3 (cryopyrin) inflammasome interleukin 1β (IL1β) pathway may offer a… Expand
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Highly Cited
2007
Highly Cited
2007
Monosodium urate crystals stimulate monocytes and macrophages to release IL-1β through the NALP3 component of the inflammasome… Expand
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Highly Cited
2004
Highly Cited
2004
OBJECTIVE To evaluate the proposed relationship between persistent reduction of serum urate into the subsaturating range and… Expand
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Highly Cited
2004
Highly Cited
2004
OBJECTIVE The use of colchicine to prevent acute gout flares during initiation of allopurinol therapy is widely practiced despite… Expand
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Highly Cited
2003
Highly Cited
2003
OBJECTIVES To analyse the clinical features and outcomes of gouty patients with concomitant septic arthritis in a medical centre… Expand
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