Substance P, human

Known as: Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2, Substance P 
Substance P (11 aa, ~1 kDa) is encoded by the human TAC1 gene. This protein plays a role in the transmission of pain, gastrointestinal smooth muscle… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1976-2018
024619762018

Papers overview

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2011
2011
Previous studies have suggested that substance P (SP) plays a critical role in the development of brain oedema and functional… (More)
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2009
2009
The distal cerebrospinal fluid-contacting neuron (dCSF-CN) is a peculiar type of neuron whose body is in the parenchyma of the… (More)
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2008
2008
Substance P (SP) is a neuropeptide associated with sensory innervation of lymphoid tissue and a suspected modulator of lymphatic… (More)
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2006
2006
Primary sensory neurons of the C and Adelta subtypes express the vanilloid capsaicin receptor TRPV1 and contain proinflammatory… (More)
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1999
1999
Substance P (SP) plays a central role in the transduction of second messenger signals from primary afferent nociceptive terminals… (More)
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Highly Cited
1998
Highly Cited
1998
Substance P, acting via the neurokinin 1 receptor (NK1R), plays an important role in mediating a variety of inflammatory… (More)
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1998
1998
The neuropeptide substance P (SP) has a marked proinflammatory effect and modulates the immune response. In this study, we tested… (More)
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1993
1993
Substance P (SP), a neurotachykinin, is important in a number of inflammatory processes in which the endothelial cell also plays… (More)
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1992
1992
Substance P (SP), a neuropeptide found in high concentrations in the gut, is reported to have many potent immunomodulatory… (More)
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1984
1984
The contractile effects of substance P (SP) were studied in isolated rabbit tracheal smooth muscle (TSM) segments in vitro… (More)
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