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Subrenal Capsule Assay

Known as: Subrenal Capsule Assays, Assay, Subrenal Capsule, Assays, Subrenal Capsule 
In vivo method of screening investigative anticancer drugs and biologic response modifiers for individual cancer patients. Fresh tumor tissue is… Expand
National Institutes of Health

Papers overview

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2005
2005
Based on previous studies, a minimal set of genetic alterations that is required to convert normal human fibroblasts into cancer… Expand
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1995
1995
In order to find out whether the response rate and survival in epithelial ovarian cancer can be improved by aid of sensitivity… Expand
Highly Cited
1987
Highly Cited
1987
Rapid in vivo growth of cultured human cancer or leukemia cells was achieved by implantation into the subrenal capsule of mice. A… Expand
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1984
1984
The subrenal capsule assay may predict to which anticancer drug a given patient's tumor is sensitive and may also be used to… Expand
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Highly Cited
1984
Highly Cited
1984
Measurement of drug activity as an oncolytic effect, use of the control only to monitor the quality of tissue implanted, and the… Expand
1984
1984
Cyclophosphamide (CY) prevented the host response from occurring in treated animals, and we therefore evaluated CY and other… Expand
1984
1984
Production of bovine müllerian inhibiting substance (MIS) has been increased to allow generation of large quantities of… Expand
Highly Cited
1983
Highly Cited
1983
Retrospective and prospective clinical trials were performed to determine the usefulness of the 6‐day subrenal capsule (SRC… Expand
1983
1983
Using the subrenal capsule assay in normal mice, a histologic evaluation was made of 8 human primary ovarian tumours and 3 human… Expand
Highly Cited
1981
Highly Cited
1981
Feasibility of utilizing human tumors as first transplant generation xenografts in the normal immunocompetent mouse for… Expand