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Subrenal Capsule Assay

Known as: Subrenal Capsule Assays, Assay, Subrenal Capsule, Assays, Subrenal Capsule 
In vivo method of screening investigative anticancer drugs and biologic response modifiers for individual cancer patients. Fresh tumor tissue is… 
National Institutes of Health

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Broader (1)

Xenograft Model Antitumor Assays
standards characteristics

Papers overview

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1998
1998
Camptothecin analogues/cisplatin: an effective treatment of advanced bladder cancer in a preclinical in vivo model system.
1995
1995
The subrenal capsule assay in selecting chemotherapy for ovarian cancer: a prospective randomized trial.
In order to find out whether the response rate and survival in epithelial ovarian cancer can be improved by aid of sensitivity… 
1990
1990
[Effects of gonadotropin on the growth of malignant ovarian neoplasms assessed by subrenal capsule assay].
In the present study 18 cases of malignant ovarian neoplasm were studied to determine the possible role of sex steroid hormones… 
Highly Cited
1987
Highly Cited
1987
Rapid growth of human cancer cells in a mouse model with fibrin clot subrenal capsule assay.
Rapid in vivo growth of cultured human cancer or leukemia cells was achieved by implantation into the subrenal capsule of mice. A… 
1987
1987
[Preclinical evaluation of a new camptothecin derivative, CPT-11, on the subrenal capsule assay].
CPT-11 is a new derivative of camptothecin, a plant alkaloid developed in Japan. We investigated the antitumor activity of CPT-11… 
Review
1985
Review
1985
The subrenal capsule assay (SRCA) and its predictive value in oncology.
: This report has been prepared as a mini-review of the studies and data, accumulated by a number of investigators since 1978… 
1984
1984
The subrenal capsule assay in mice. Prediction of rat tumor sensitivity to chemotherapy
The predictive value of the subrenal capsule (SRC) assay for cancer chemotherapy was tested in five rat tumors. Tumor‐bearing… 
1984
1984
Comparison of the human tumor cloning and subrenal capsule assays.
Fresh surgical explants of solid tumors obtained from 84 patients were tested against the same chemotherapeutic agents in both… 
Highly Cited
1983
Highly Cited
1983
Initial clinical trials of the subrenal capsule assay as a predictor of tumor response to chemotherapy
Retrospective and prospective clinical trials were performed to determine the usefulness of the 6‐day subrenal capsule (SRC… 
1983
1983
Single agent chemotherapy for head and neck cancers. The murine subrenal capsule assay.
The murine subrenal capsule assay was used to determine chemotherapeutic sensitivities of metastatic, primary, or recurrent head… 
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