Xenograft Model Antitumor Assays

Known as: Xenograft Antitumor Assay, Assays, Xenograft Antitumor, Xenograft Antitumor Assays 
In vivo methods of screening investigative anticancer drugs, biologic response modifiers or radiotherapies. Human tumor tissue or cells are… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
PURPOSE Cancer stem cells (CSC) are the tumorigenic cell population that has been shown to sustain tumor growth and to resist… (More)
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Highly Cited
2012
Highly Cited
2012
The ability to track microbes in real time in vivo is of enormous value for preclinical investigations in infectious disease or… (More)
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Highly Cited
2012
Highly Cited
2012
PURPOSE To understand the role of HER2-associated signaling network in breast cancer stem cells (BCSC) using radioresistant… (More)
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Highly Cited
2011
Highly Cited
2011
Temozolomide (TMZ) is an alkylating agent used for treating gliomas. Chemoresistance is a severe limitation to TMZ therapy; there… (More)
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Review
2010
Review
2010
Approximately two million fractions of radiotherapy are administered in the UK every year, as part of adjuvant, radical or… (More)
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Highly Cited
2009
Highly Cited
2009
Tumour growth and spread of tumour cells requires angiogenesis. Incipient angiogenesis is not induced by tumour cell hypoxia but… (More)
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2009
2009
Tumor development is a complex and dynamic process that involves malignant, vascular, and stromal cells. Endosialin is a tumor… (More)
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Highly Cited
2003
Highly Cited
2003
Activation of the Hedgehog (Hh) signalling pathway by sporadic mutations or in familial conditions such as Gorlin's syndrome is… (More)
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2003
2003
Oncolytic adenoviruses are being tested as biological cancer therapeutics. Ar6pAE2fF (E2F vector) contains the E2F-1 promoter to… (More)
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Highly Cited
1987
Highly Cited
1987
Taxol, a plant product, has significant activity against certain rodent and human xenograft tumors. It promotes microtubule… (More)
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